Clinician's Pocket Drug Reference 2008

Moxifloxacin 147D 2nd & 3rd tri), ?] Contra: ACE inhibitor sensitivity Disp: Tabs 7.5, 15 mg; SE:↓ BP, edema, angioedema, HA, dizziness, coughMolindone (Moban) Uses: *Psychotic disorders* Action: Piperazine phenothiazineDose: Adults. 50–75 mg/d PO,↑ to max of 225 mg/day at 3–4 day intervalsif necessary. Peds. 3–5 y: 1–2.5 mg/d PO in 4 ÷ doses. 5–12 y: 0.5–1.0mg/kg/d in 4 ÷ doses Caution: [C, ?] NAG Contra: Drug/EtOH CNS depressionDisp: Tabs 5, 10, 25, 50 mg; SE: ↓ BP, tachycardia, arrhythmias, EPS, Szs, constipation,xerostomia, blurred vision. Notes: Monitor lipid profile, fasting glucose,HgB A1-cMontelukast (Singulair) Uses: *Prophylaxis & Rx of chronic asthma,seasonal allergic rhinitis* Action: Leukotriene receptor antagonist Dose: Asthma:Adults & Peds > 15 y. 10 mg/d PO taken in PM. Peds. 2–5 y: 4 mg/d PO taken inPM. 6–14 y: 5 mg/d PO in PM. Caution: [B, M] Contra: Component allergyDisp: Tabs 10 mg; chew tabs 4, 5 mg; granules 4 mg/packet SE: HA, dizziness, fatigue,rash, GI upset, Churg–Strauss synd Notes: Not for acute asthmaMorphine (Avinza XR, Duramorph, Infumorph, MS Contin,Kadian SR, Oramorph SR, Infumorph, Roxanol) [C-II] Uses:*Relief of severe pain* AMI Action: Narcotic analgesic Dose: Adults. PO: 5–30mg q4h PRN; SR tabs 15–60 mg q8–12h (do not chew/crush). IV/IM: 2.5–15 mgq2–6h; supp 10–30 mg q4h. IT: (Duramorph, Infumorph): Per protocol Peds.> 6 mo 0.1–0.2 mg/kg/dose IM/IV q2–4h PRN to 15 mg/dose max; 0.2–0.5 mg/kgPO q 4–6h prn; 0.3–0.6 mg/kg SR tabs PO q12h; 2–4 mg IV (over 1–5 min) every5–30 min (ECC 2005) Caution: [B (D w/prolonged use/high doses at term), +/–]Contra: Severe asthma, resp depression, GI obst Disp: Immediate-release tabs 10,15, 30 mg; MS Contin CR tabs 15, 30, 60, 100, 200 mg; Oramorph SR CR tabs 15,30, 60, 100 mg; Kadian SR caps 20, 30, 50, 60, 80, 100 mg; Avinza XR caps 30,60, 90, 120 mg; soln 10, 20, 100 mg/5 mL; supp 5, 10, 20, 30 mg; inj 2, 4, 5, 8, 10,15, 25, 50 mg/mL; Duramorph/Astramorph inj 0.5, 1 mg/mL; Infumorph 10, 25mg/mL, supp 5, 10, 20, 30 mg SE: Narcotic SE (resp depression, sedation, constipation,N/V, pruritus), granulomas w/ IT Notes: May require scheduled dosing torelieve severe chronic pain; do not crush/chew SR/CR formsMorphine liposomal (DepoDur) Uses: *Long-lasting epidural analgesia*Action: ER morphine analgesia Dose: 10–20 mg lumbar epidural inj (C-section10 mg after cord clamped) Caution: [C,+/–] elderly, biliary Dz (sphincter ofOddi spasm) Contra: Ileus, resp depression, asthma, obstructed airway, suspected/knownhead injury ↑ ICP, allergy to morphine. Disp: Inj 10 mg/mL SE:Hypoxia, resp depression, ↓ BP, retention, N/V, constipation, flatulence, pruritus,pyrexia, anemia, HA, dizziness, tachycardia, insomnia, ileus Notes: Effect ≤48 h;not for IT/IV/IMMoxifloxacin (Avelox, Vigamox ophthalmic) Uses: *Acute sinusitis& bronchitis, skin/soft tissue Infxns, conjunctivitis, & community-acquiredpneumonia* Action: 4th-gen quinolone; ↓ DNA gyrase. Spectrum: Excellent gram