Pharmakologie der ADP-Rezeptoren auf humanen Thrombozyten
Pharmakologie der ADP-Rezeptoren auf humanen Thrombozyten
Pharmakologie der ADP-Rezeptoren auf humanen Thrombozyten
Erfolgreiche ePaper selbst erstellen
Machen Sie aus Ihren PDF Publikationen ein blätterbares Flipbook mit unserer einzigartigen Google optimierten e-Paper Software.
46. Garcia, A., A.B. Galler, U. Walter, M. Reinhard, and A. Simm. 2002. Increased Spreading, Rac/p21activated<br />
Kinase (PAK) Activity, and Compromised Cell Motility in Cells Deficient in<br />
Vasodilator-stimulated Phosphoprotein (VASP). J Biol Chem 277:45604-45610.<br />
47. Gawaz, M. 1999. Das Blutplaettchen. Georg Thieme Verlag<br />
48. Geiger, J., J. Brich, L. Honig, M. Eigenthaler, P. Schanzenbacher, J.M. Herbert, and U. Walter. 1999.<br />
Specific impairment of human platelet P2Y(AC) <strong>ADP</strong> receptor-mediated signaling by the<br />
antiplatelet drug clopidogrel. Arterioscler Thromb Vasc Biol 19:2007-2011.<br />
49. Geiger, J., L. Honig, P. Schanzenbacher, and U. Walter. 1998. Ligand specificity and ticlopidine<br />
effects distinguish three human platelet <strong>ADP</strong> receptors. Eur J Pharmacol 351:235-246.<br />
50. Geiger, J., C. Nolte, E. Butt, S.O. Sage, and U. Walter. 1992. Role of cGMP and cGMP-dependent<br />
protein kinase in nitrovasodilator inhibition of agonist-evoked calcium elevation in human<br />
platelets. Proc Natl Acad Sci U S A 89:1031-1035.<br />
51. Geiger, J., C. Nolte, and U. Walter. 1994. Regulation of calcium mobilization and entry in human<br />
platelets by endothelium-<strong>der</strong>ived factors. Am J Physiol 267:C236-C244<br />
52. Geiger, J. and U. Walter. 1993. Properties and regulation of human platelet cation channels. EXS<br />
66:281-288.<br />
53. Gent, M., J.A. Blakely, J.D. Easton, D.J. Ellis, V.C. Hachinski, J.W. Harbison, E. Panak, R.S. Roberts,<br />
J. Sicurella, and A.G. Turpie. 1989. The Canadian American Ticlopidine Study (CATS) in<br />
thromboembolic stroke. Lancet 1:1215-1220.<br />
54. Greco, N.J., G. Tonon, W. Chen, X. Luo, R. Dalal, and G.A. Jamieson. 2001. Novel structurally<br />
altered P(2X1) receptor is preferentially activated by adenosine diphosphate in platelets and<br />
megakaryocytic cells. Blood 98:100-107.<br />
55. Grundmann, K., K. Jaschonek, B. Kleine, J. Dichgans, and H. Topka. 2003. Aspirin non-respon<strong>der</strong><br />
status in patients with recurrent cerebral ischemic attacks. J Neurol 250:63-66.<br />
56. Gurbel, P.A., C.C. Cummings, C.R. Bell, A.B. Alford, A.F. Meister, and V.L. Serebruany. 2003. Onset<br />
and extent of platelet inhibition by clopidogrel loading in patients un<strong>der</strong>going elective<br />
coronary stenting: the Plavix Reduction Of New Thrombus Occurrence (PRONTO) trial. Am<br />
Heart J 145:239-247.<br />
57. Habib, A., G.A. FitzGerald, and J. Maclouf. 1999. Phosphorylation of the thromboxane receptor alpha,<br />
the predominant isoform expressed in human platelets. J Biol Chem 274:2645-2651.<br />
58. Halbrugge, M., C. Friedrich, M. Eigenthaler, P. Schanzenbacher, and U. Walter. 1990. Stoichiometric<br />
and reversible phosphorylation of a 46-kDa protein in human platelets in response to cGMP-<br />
and cAMP-elevating vasodilators. J Biol Chem 265:3088-3093.<br />
59. Halbrugge, M. and U. Walter. 1989. Purification of a vasodilator-regulated phosphoprotein from<br />
human platelets. Eur J Biochem 185:41-50.<br />
60. Hall, R.A., L.S. Ostedgaard, R.T. Premont, J.T. Blitzer, N. Rahman, M.J. Welsh, and R.J. Lefkowitz.<br />
1998. A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic<br />
fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger<br />
regulatory factor family of PDZ proteins. Proc Natl Acad Sci U S A 95:8496-8501.<br />
61. Harbeck, B., S. Huttelmaier, K. Schluter, B.M. Jockusch, and S. Illenberger. 2000. Phosphorylation of<br />
the vasodilator-stimulated phosphoprotein regulates its interaction with actin. J Biol Chem<br />
275:30817-30825.<br />
107