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Coordinated regulation of gene expression by E ... - Jacobs University

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LIST OF FIGURES<br />

List <strong>of</strong> Figures<br />

Figure 1: Schematic illustration <strong>of</strong> operation <strong>of</strong> the <strong>gene</strong>tic system involving an<br />

alternation <strong>of</strong> the digital (discontinuous) and analog (continuous) information. ... 4<br />

Figure 2: Structure <strong>of</strong> consensus Eσ70 promoter showing functionally important<br />

region. ……………………………………………………………………………… 6<br />

Figure 3: Structural pr<strong>of</strong>iles <strong>of</strong> Sigma70 and Sigma54 promoter regions. …….. 7<br />

Figure 4: In vitro transcription from fis & bla promoters at different superhelical<br />

densities …………………………………………………………………………….. 8<br />

Figure 5: Schematic representation <strong>of</strong> core promoters with different spacer<br />

length. ……………………………………………………………...………………... 9<br />

Figure 6: Graphical representation <strong>of</strong> global DNA topology changing with growth<br />

......................................................................................................................................... 12<br />

Figure 7: Abundance <strong>of</strong> NAPs during different phases <strong>of</strong> growth . ........................ 13<br />

Figure 8: Growth phase-dependent change in the level <strong>of</strong> different forms <strong>of</strong> the<br />

RNA polymerase.. ......................................................................................................... 15<br />

Figure 9: Overview <strong>of</strong> comparative <strong>gene</strong> <strong>expression</strong> <strong>of</strong> wild-type & fis (example)<br />

analysis using microarrays. .......................................................................................... 29<br />

Figure 10: Growth curves <strong>of</strong> CSH50 wild-type and the mutants. ........................... 35<br />

Figure 11: Design <strong>of</strong> DNA microarray experiments. ................................................ 37<br />

VI

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