DR Medhat MRCP

Lung carcinoid
- Neuro-endocrine tumor arising from Kulchitsky (K)cell [cells from amine precursor
uptake and decarboxylation (APUD) system].
- The vast majority of bronchial adenomas are carcinoid tumours
- Lung carcinoid accounts 1% of lung tumours and for 10% of carcinoid tumours.
• Features
Typical age = 40-50 years
Site : main bronchi ; most frequently in RT middle lobe .
Smoking not risk factor
Slow growing: e.g.
- long history of cough, recurrent haemoptysis
- intestinal cramps & diarrhoea
Often centrally located and not seen on CXR
Highly vascular : 'Cherry red ball' often seen on bronchoscopy (pathognomonic)
Carcinoid syndrome itself is rare (associated with 5% of liver metastases).
سؤال : choice • Investigation of
Bronchoscopy & biopsy
- Bronchoscopy identifies up to 80% of carcinoid tumors in the main bronchi
- Biopsy is usually followed with brisk bleeding and should be done via rigid
bronchoscopy.
• Management
Surgical resection
• Prognosis : if no metastases then 90% survival at 5 years.