11.03.2017 Views

DR Medhat MRCP

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■ Diagnosis :<br />

■ Treatment :<br />

Karyotype analysis → 15,XO<br />

Gonadal (hormone replacement therapy)<br />

o Estrogen :<br />

- Should be started at early stages in low doses then gradually ↑ dose<br />

over 1-2 years then maintenance ttt lifelong.<br />

- It will promote development of 2ndry sex characters.<br />

o Growth hormone :<br />

- It may help in ↑ the hight of the child with Turner`s syndrome<br />

although she has no GH deficiency.<br />

Since the patient has no internal genitalia (gonads),FSH & LH have no role in ttt<br />

سؤال ttt. of Turner`s syndrome. Also progesterone has no role in<br />

Bicuspid aortic valve (15%) is the commonest cardiac abnormality in Turner`s<br />

syndrome then coarctation of the aorta (5-10%).<br />

<br />

Polycystic ovary syndrome (PCOS)<br />

سؤال<br />

- Hirsutism<br />

- Acanthosis nigricans<br />

- Acne<br />

- Secondary amenorrhoea<br />

- Infertility<br />

- Obesity<br />

- Ultrasound is the test of choice<br />

- ↑ LH/FSH ratio

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