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DR Medhat MRCP

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Cohort study<br />

• Def :<br />

- It`s an observational study of a group of subjects with specific disease or<br />

characteristic (e.g smokers) who are followed up over a period of time to detect<br />

complications or new events.<br />

- This group may be compared with control group (e.g non-smokers).<br />

- If this type of study requires follow up over several years , it may be prone to loss<br />

of subjects.<br />

- Persons exposed (a+b) to the suspected cause and those not exposed (c+d) are<br />

followed prospectively over time to determine the rate of a disease or specific<br />

event.<br />

Incidence rate of outcome in the exposed group =<br />

Incidence rate of outcome in non-exposed group =<br />

126

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