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DR Medhat MRCP

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سؤال امتحان classification) • Assessment of severity of liver cirrhosis (Child-Pugh<br />

Score 1 2 3<br />

Bilirubin (µmol/l) 50<br />

Albumin (g/l) >35 28-35 9 = C<br />

• Investigations : see child`s staging + U.S.+ ascetic tapping.<br />

• Complications :<br />

1) Coagulopathy (bleeding tendency) [↓ clotting factors synthesis + ↓ platelets+↓<br />

vit K]<br />

2) Encephalopathy [ NH3,aromatic chain aa, enteric bacteria pass unchanged<br />

through the liver or bypass the liver to the brain].<br />

3) Ascites (portal HTN + Hypoalbuminemia].<br />

4) Spontaneous bacterial peritonitis [on top of ascitis]→ TTT : Cefotaxime<br />

5) Hepatorenal syndrome.<br />

6) Cachexia<br />

7) Hepatocellular carcinoma.<br />

• Management :<br />

General measures :<br />

1) Ascites : diuretics (spironolactone)<br />

2) Portal HTN : non-selective BB (propranolol).<br />

TTT of complications<br />

سؤال<br />

77

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