DR Medhat MRCP

Management
Minimal change glomerulonephritis - prednisolone
1 ST line TTT : Steroids:
- Prednisolone 1mg/kg/d. maximum 60 mg/day until remission is achieved (at
least 12 weeks to risk of relapse) then,
- Gradual tapering (over 6 months) :1 st , fortnightly (i.e once after 2 weeks),then
weekly until discontinued.
2 nd line TTT according to steroid respose :
A. For 1 st relapse or infrequent relapses :
- repeat the same steroid regimen (we can start with I.V pulse methyl
prednisone 1g/d X3 days then PO prednisolone & taper immediately once
remission occur to avoid prolonged steroid courses).
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