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DR Medhat MRCP

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سؤال هام فى االمتحان : pupil • Disorders of the<br />

A. Miosis (small pupil) :<br />

Causes :<br />

1. Horner`s syndrome.<br />

2. Argyll-Robertson pupil.<br />

3. Congenital miosis.<br />

4. Senile miosis.<br />

5. Pinpoint pupil (pontine hge,opiate toxicity,organophosphorus poison)<br />

Horner`s syndrome (sympathetic lesion) :<br />

- Ptosis (partial)<br />

- Miosis .<br />

- Anhydrosis<br />

- Enophthalmos<br />

- Lost spino-ciliary reflex<br />

( normally ,bricking one side of the neck<br />

ipsilateral mydriasis).<br />

Left side Horner`s syndrome<br />

(ptosis +miosis)<br />

• Distinguishing it from other causes:<br />

o Heterochromia (i.e difference<br />

In iris colour) : in congenital<br />

Horner.<br />

notice the heterochromia (congenital)<br />

o Anhydrosis can determine the site of lesion in Horner`s syndrome :<br />

Central lesion Preganglionic lesion Postganglionic lesion<br />

Anhydrosis Face,arm&trunk Only face No anhydrosis<br />

Causes 1. Stroke.<br />

2. Syringomyelia.<br />

3. Multiple sclerosis<br />

4. Encephalitis.<br />

5. Tumors<br />

1. Pancoast tumor.<br />

2. Thyroidectomy.<br />

3. Trauma.<br />

4. Cervical rib.<br />

1. Carotid artery dissection.<br />

2. Carotid aneurysm.<br />

3. Cavernous sinus thrombosis.<br />

4. Cluster headache.<br />

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