DR Medhat MRCP

B. Skin manifistations :
1. Malar flush (butterfly rash).
2. Discoid rash (red ,scaly, on cheeks & nasal bridge)
3. Photosessitivity.
4. Oral ulcers.
5. Nailfolds infarcts.
6. Livido-reticularis
7. Raynaud`s phenomenon.
C. Musculoskeletal :
Malar flush
1. Symmetrical polyarthralgia & polyarthritis.
2. Proximal myopathy.
D. Pulmonary :
1. Pleurisy & pleural effusion.
2. Lupus pneumonitis.
E. Heart :
1. Pericardidis & pericardial effusion.
2. Myocarditis .
3. Libman-sack`s endocarditis (affecting mainly mitral valve MR).
F. GIT :
1. Peritonitis.
2. Mesenteric vasculitis.
3. Acute pancreatitis.
G. Renal :
Discoid rash
Lupus nephritis (proteinuria , microscopic hematuria)
1. Class I : no glomerular abnormality.
2. Class II : mesangio-proliferative GN with IgG,IgM &C3 deposites
3. Class III : focal proliferative GN.
4. Class IV : membranous GN.
5. Class V: total glomerulosclerosis.
H. Hematological :
1. Pancytopenia.
I. Ocular :
1. Conjunctivitis.
2. Episcleritis
3. Scleritis
4. Uveitis.
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