DR Medhat MRCP

Respiratory questions reveiw for MRCP
Q1 : In restrictive lung disease due to respiratory muscle weakness, which of the
following statements is true?
1- Low FEV1/FVC, high RV/TLC
2- Low FEV1/FVC, normal TLC
3- Low VC, low FEV1, normal TLC, low RV/TLC
4- Low VC, low RV, low TLC
5- Low VC, low TLC, high RV/TLC
Answer: 5- Low VC, low TLC, high RV/TLC
The lung is itself can function normally yet muscle weakness will result in grossly low lung
volumes including FEV1, FVC and TLC. However residual volume will be relatively high as a
consequence of this weakness. Consequently, RV/TLC will be elevated. However the
transfer of carbon monoxide (TCO) will be unaffected.
Q2 : Which of the following is found in subjects acclimatised to life at high altitudes ?
1- Increased mean corpuscular haemoglobin concentration
2- Increased pulmonary artery pressure
3- Periodic respiration
4- Reduced cardiac output
5- Reduced airway resistance
Answer: 2- Increased pulmonary artery pressure
discriminating question!
- Acclimatisation results in increased Hb with erythrocytosis.
- Periodic respiration is a feature of non-acclimatisation.
- Respiration is normal when subjects are acclimatised to altitude as is cardiac output.
- Pulmonary artery presure increases in an effort to oxygenate more blood.
- 2,3-DPG increases.
Q3 : Most of the cells that fill the alveoli in desquamative interstitial pneumonitis
(DIP) are which of the following?
1- Eosinophils
2- Lymphocytes
3- Macrophages
4- Neutrophils
5- Plasma cells
Answer: 3- Macrophages