DR Medhat MRCP

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Eosinophil Basophil Neutrophil Macrophage Monocyte Lymphocyte B-cells T-cells NK-Cells Mast cells Classification Function /Target pathogen Mode of action Mobile/static Diagram Granular leucocytes Granular leucocytes Granular leucocytes Granular leucocytes Agranular leucocytes lymphocytes lymphocytes - Deals with parasitic infection. - Modulate allergic inflammatory response e.g BA, Hay fever - Release of histamine for inflammatory response. - Attacks bacterial & fungal cells - Most common cell seen in early acute inflammation - Life span 4-5 days. - Pathogen & cellular debris phagocytosis. - Antigen presenting cells & ++ of T-cells. Degranulation Degranulation Phagocytosis Phagocytosis Mobile Mobile Mobile Both - Migrate from blood to tissues where it differentiates into tissue macrophages ( Kupffer cells in liver) & dendritic cells Phagocytosis Mobile 1. Release of antibodies 2. Help in ++ of T-cells. Degranulation Mobile 1. CD4 (T-helper cells) ++ B &T cells 2. CD8 (cytotoxic T-cells) : virus-infeted & tumour cells 3. Suppressor T- cells resume normal immunity after dealing with infection to prevent autoimmunity. Cytokine production Mobile lymphocytes virus-infected & tumour cells. Phagocytosis Mobile Granular leucocytes Release of histamine Degranulation Static
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A-PDF Merger DEMO : Purchase from w
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It contains : - 46 (23 pairs) of ch
Page 5 and 6: 6. Glycolipids - signal molecules.
Page 7 and 8: Eukaryotic cell cycle : - Human bod
Page 9 and 10: • Regulation of the cell cycle :
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Page 13 and 14: • Morphology of apoptosis (EM) :
Page 16 and 17: Ion transport - Trans-membrane ion
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Page 20 and 21: 20
Page 22 and 23: 22
Page 24: Disease Signal transduction Ligands
Page 27 and 28: Example of GP-CR → Adrenergic rec
Page 29 and 30: 29
Page 31 and 32: - There are around 30,000 gene , on
Page 33 and 34: - The language used by DNA is calle
Page 35 and 36: Autosomal dominant Autosomal recess
Page 37 and 38: Modes of disease inheritance Autos
Page 39 and 40: Autosomal dominant conditions Very
Page 41 and 42: X-linked dominant inheritance - The
Page 43 and 44: Fragile X syndrome : - Trinucleotid
Page 45 and 46: Some common genetic syndromes Triso
Page 47 and 48: Edwards Syndrome - Also known as Tr
Page 49 and 50: • Prognosis of Marfan syndrome -
Page 51 and 52: Noonan Syndrome - Often thought of
Page 53 and 54: Immune system - Immunity is the lin
Page 55: Classification of immunity Innate i
Page 60 and 61: Some plasma proteins with important
Page 62 and 63: هام جدا ‏)يحفظ صم(‏
Page 64 and 65: o Plasma cell : which will secrete
Page 66 and 67: o Ig has 2 sides, 1 st one is the a
Page 68 and 69: Rheumatoid Factor (RF) Rheumatoid f
Page 70 and 71: 70
Page 72 and 73: Causes of hypocomplementaemia : Abn
Page 74 and 75: Anti-inflammatory drugs : 1- Non-st
Page 76 and 77: Corticosteroids : Action Immunosupp
Page 78 and 79: E. Other cytotoxic drugs Cytotoxic
Page 80 and 81: Polyclonal antibodies Thymoglobulin
Page 82 and 83: سؤال هام جدا : Hypersensi
Page 84 and 85: Acid-base balance & its disturbance
Page 86 and 87: Normal anion gap (hyperchloraemic)
Page 88 and 89: Clinical picture of metabolic acido
Page 90 and 91: o Treatment of acute respiratory ac
Page 92 and 93: o Management of metabolic alkalosis
Page 94 and 95: Hyponatremia - May be caused by wat
Page 96 and 97: B) TTT of hyponatremia without ence
Page 98 and 99: Correction of hypernatremia : Aim
Page 100 and 101: o Treatment of hyperkalemia : 1. I.
Page 102 and 103: Hypomagnesemia: o Cause of low magn
Page 104 and 105: A. Statistics which describe data P
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MODE • Def : the mode is the most
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Statistics which analyze relationsh
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Q : 110
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Q : Non-parametric tests Analysis
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- The statistician has combined the
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Statistics which compare risk RISK
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Q3 MI (event rate ER) No MI Blacebo
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Statistics which analyze clinical i
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Q : Whether a test is clinically v
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Clinical study design - It`s the fo
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Cohort study • Def : - It`s an ob
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Cohort study Suitable for common d
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- If a drug is therefore to be comp
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1
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Pathology myocardium Clinical syndr
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Arterial supply of the heart (coron
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Recurrent chest pain History & exam
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Method: Percutaneous coronary inter
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Acute coronary syndrome Acute chest
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The table below summaries the mecha
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• Complications of backward tear
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Supraventricular tachycardia (SVT)(
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Clinical picture : Symptoms 1. Palp
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Management of AF : o The main goals
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Decision of long-term anticoagulati
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Atrial flutter Tachycardia with a r
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Ventricular tachycardia (VT) - VT i
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Wolff-Parkinson White syndrome(WPW)
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Prolonged PR interval (=1st degree
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33
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• Treatment of non-shockable rhyt
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• Indications for a temporary pac
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Normal ECG waves In an athlete: Si
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Heart failure • NYHA (New York He
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Hypertension • Classification :
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45
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Pre-eclampsia : - ∆ of HTN (> 140
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Heart sounds S1 During ventricular
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Arterial pulse waveform & its abnor
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'A' wave = Atrial contraction Larg
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Types Disadvantages Advantages Indi
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سؤال • Treatment : Aortic val
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59
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61
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Cardiac tamponade - i.e Accumulatio
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Hypertrophic obstructive cardiomyop
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Arrhythmogenic right ventricular ca
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Acyanotic congenital heart disease
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Coarctation of the aorta - Coarctat
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اليخلو منها امتحان
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• Basics : Deoxygenated blood re
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Later complications 1. Subfertility
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Prognosis of Marfan syndrome: - The
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Investigations : - Blood culture (3
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B) Surgical ttt : ‣ Indications :
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Class I Na + channel Blockers Class
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Flecainide : Class : class Ic anti
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Angiotensin converting enzyme inhib
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1) Hyperventilation( + + RC) & resp
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1
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Pruritus - The table below lists th
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• Clinical presentation : Blackh
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Pityriasis rosea - Common harmless
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Psoriasis - Psoriasis is a common c
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Eczema (dermatitis) - Eczema is an
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C. Seborrhoeic eczema/dermatitis -
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Bullous disorders (i.e causes of sk
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Dermatitis herpetiformis - Is an au
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• Treatment : No specific therapi
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Drug eruptions - Skin reaction deve
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Licnen planus : purple,pruritic,pop
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4. The BNF advises to apply the ins
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Alopecia (hair loss or baldness) -
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Fungal nail infections (Onychomycos
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Tinea capitis Tinea corporis Tinea
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Porphyria - The porphyrias are a gr
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Erythrasma - Is a generally asympto
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Venous Ulceration - Is typically se
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Skin disorders associated with TB
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Vitiligo - It is the most common de
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Hormones of pituitary gland :
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Anterior pituitary diseases Hypopiu
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Investigations : 1) Basal hormone l
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Investigations : 1) GH level in the
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• Treatment : First line of ttt i
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o Bromocriptine (parlodil) : - Star
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DIABETES INSIPIDUS (DI) - Polyuria
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Polyuria-polydipsia High urine SG L
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3) Neurological : - Stroke . - Suba
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اللهم السهل االماج
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Synthesis & release of thyroid horm
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C/P of hyperthyroidism : o Symptoms
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Differences () Grave`s disease & ot
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III. Radioiodine treatment It dest
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سؤال Pendred's syndrome - Auto
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Myxoedema coma : - It`s a life-thre
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1) Levothyroxine(Eltroxin) : - Init
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Thyroid diseases & pregnancy - In p
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سؤال : cancer • Poor prognost
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Calcium homeostasis : Calcium homeo
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Hypocalcemia - Decrease plasma Ca l
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Management of hypocalcemia : ■ Ac
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■ Management of hypercalcemia : A
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6) Technetium-MIBI subtraction scan
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Diagnosis : by measuring urinary cA
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Osteoporosis Def : low bone mass (
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1) Bisphosphonates : - Alendronate
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Treatment 1. Bisphosphonate (either
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B. C/P of osteomalacia (i.e in adul
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Adrenal(supra-renal) glands Anatom
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Aldosterone Diseases of adrenal gla
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• Management of 1ry hyperaldoster
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High ACTH (ACTH dependent) Test Met
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Features : Lethargy, weakness, ano
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o Signs (=features of sympathetic o
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Clinical presentation of DM : Clas
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Risk factors for cardiovascular dis
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Oral glucose-lowering drugs 1) Insu
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NB : Dipeptidyl Peptidase-4 (DPP-4)
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A. For twice daily regimens : - The
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Normal fundus Background diabetic r
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Diabetic amytrophy (amyotrophy= prg
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Diabetic ketoacidosis (DKA) Def: l
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- Very sick pt with severe acidosis
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6. Postnatal adaptation problems (e
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Def: plasma glucose < 4mmol/L. Cau
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Metabolic Syndrome - Syndrome consi
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II. Psychological : - Anxiety /depr
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2) Patients with a BMI > 40 kg/ m2
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- HMG-CoA reductase (or 3-hydroxy-3
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Eruptive xanthoma Palmar xanthoma -
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Primary prevention Secondary preven
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• Female menstrual cycle :
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• Diagnosis of delayed puberty :
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Male hypogonadism : ■ Causes : 1r
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Female hypogonadism : Amenorrhoea
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■ Diagnostic approach of primary
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Hormone results Possible diagnosis
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Turner`s Syndrome - Is a chromosoma
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■ Def : - Ovarian dysfunction of
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Multiple endocrine neoplasia (MEN)
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Corticosteroids : - The relative gl
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Digestive system 2
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Oesophageal diseases Oesophageal va
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Gastro-oesophageal reflux disease(G
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Management of endoscopy proven GERD
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Achalasia - Failure of esophageal p
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• Causes : 1. Iatrogenic (post en
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• Treatment : 1) Palliative oesop
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• Management of dyspepsia : (NICE
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Management of endoscopy proven GERD
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Proton pump inhibitor doses relatin
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❖ MALT(mucosa-associated lymphoid
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Drug Adverse effects Interacting dr
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• Clinical picture : 1) Fat absor
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• Pathogenesis : - Ingestion of g
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سؤال : atrophy Causes of villou
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Whipple`s disease - It`s a rare mul
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Colorectal carcinoma - Cancerous gr
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• Clinical picture : 1) Change in
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Diverticular disease (diverticulosi
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• Features 1) Hamartomatous polyp
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سؤال ): st Red flag features s
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• Differences between crohn`s dis
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• Management of IBD : A. Manageme
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Maintaining remission of UC : Mild
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Diarrhea • Def : - Abnormal passa
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هام جدا : picture • Clinica
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Clostridium difficile: - Is a Gram
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• General features of hepatitis :
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Extra-hepatic manifestations of chr
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Marker Appear in blood After infect
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• Complications of hepatitis B in
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• Investigations : Alcoholic stea
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Non-alcoholic steatohepatitis (NASH
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Hereditary hepatitis Wilson`s disea
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Alpha-1 antitrypsin deficiency - Al
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Primary biliary cirrhosis - Is a ch
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Primary sclerosing cholangitis (PSC
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• Clinical picture : - Most of CL
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Ascites : - i.e accumulation of flu
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• Features : Tends to present la
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- In upright position→ ↑ blood
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• Investigations : LFT . EEG.
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• Clinical picture (=complication
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Jaundice • Def : yellow discolora
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Liver function tests : Blood test T
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Rotor syndrome: - Is a rare, relati
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• Assessment of severity of acute
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Cysts: - Cystic tumour can occur in
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Acetylcysteine should be given if:
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1
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Macrocytic The MOST Suggestive feat
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• Investigations : CBC : - Micro
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Hb-A (α2β2) Hb-A2 (α2 2) Hb-F (
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β thalassemia (= Mediterranean or
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• Diagnostic tests : Molecular g
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Treat any underlying cause سؤال
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Tips: ABO antigens are present fro
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Paroxysmal nocturnal hemoglobinuria
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Microangiopathic hemolytic anemia (
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Disseminated intravascular coagulop
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• Presentation : Failure to thri
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Hemolytic crises : Rare in sicklers
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Myelofibrosis - Myeloproliferative
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• TTT : Elderly patients (the ma
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Polycythemia • Def : - ↑ Of RBC
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• Diagnosis of PRV (revised WHO c
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• Causes : A. Congenital causes :
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Neutrophils > 7 X 10*9/l Neutrophi
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Eosinophilia • Causes : - A usefu
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Monocytosis 1) Infection Bacterial
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Haematological malignancies - Group
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• Diagnosis: CBC : leucocytosis
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سؤال • Diagnosis: Differentia
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• Diagnosis: Philadelphia is con
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• Management Patients not indica
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Malignant lymphomas Hodgkin's Lymph
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Nodular sclerosing subtype Mixed ce
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• Diagnosis : Lymph node biopsy
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Paraproteinemia = monoclonal gammop
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• Management of MM: 1) Induction
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Vaccination in a case of hypospleni
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• Clinical picture : Ranges from
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• Classification of bleeding diso
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Haemophilia - Haemophilia is a X-li
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Heparin-induced thrombocytopaenia (
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• TTT of Warfarin overdose : Majo
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75
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Condition PT/INR APTT Bleeding time
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• Management : lifelong warfarin
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Leucocyte alkaline phosphatase •
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ONCOLOGY Cancer in the UK • The m
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Cytotoxic drugs - Cytotoxic drugs a
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E. Other cytotoxic drugs Cisplatin
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Palliative care prescribing: pain N
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Hormone replacement therapy • Ind
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Prostatic tumours 1. Benign prostat
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Bladder cancer • Risk factors Sm
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1
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Anaerobes Aerobes α-hemolytic stre
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Antibiotics and aerobics/anerobics
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Tetanus vaccine: - Is a detoxified
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MRSA : Methicillin-resistant Staphy
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C. Clostridium - G+ve anaerobic bac
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G -ve bacteria G-ve Cocci Neisseri
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Legionnaire's disease - Is caused b
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• Clinical picture : A. Latent (i
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2) Heaf test (no longer used in UK)
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II. Mycobacterium leprae Leprosy:
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Lyme disease (Borreliosis) : B. Bor
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Protozoal diseases I. Malaria - Mal
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• Prophylaxis of malaria ( for pe
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II. Leishmaniasis - Leishmania is a
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B. American trypanosomiasis, or Cha
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Viral infections 1) HIV - HIV is a
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- Extra-pulmonary manifestations of
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سؤال هام جدا Neurologica
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• HIV in pregnancy : - 0.4% of pr
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DD : Molluscum contagiosum. - Mollu
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• Treatment : Oseltamivir (Tamif
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7) Dengue fever - Is a type of vira
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Helmenthic diseases A. Nematodes (H
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Gonorrhoea (discussed before) Chla
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Vaginal discharge : - Vaginal disch
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- Diagnosis of syphilis (based on C
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Anthropodes Scabies - Scabies is ca
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G +ve bacilli Actinomycosis Bacillu
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TTT of cryptosporidium diarrhea : m
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Ribavirin Guanosine analog Chronic
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Pelvic inflammatory disease : - Pel
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Splenectomy - Following a splenecto
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2
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Classification of renal diseases I.
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II. According to pathogenesis A) Im
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8
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Renal parechymatous diseases Glome
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12
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B. For frequent relapses,steroid de
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Investigations : SCr, eGFR, U&E, a
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Management : 1 st line TTT is ster
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Membranoproliferative(= Mesangiocap
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Investigations : Routine SCr, eGFR
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Histopathology of MCGN : 1) Type I
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N.B : C3 glomerulopathy Isolated
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Presentation: Proteinuria ( nephro
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Immune suppression in MN : 1 ST li
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Diffuse proliferative glomeruloneph
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Investigations: SCr, U&E, eGFR, se
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Differentiating between IgA nephrop
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Nephritic syndrome Def : Clinical s
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Investigations : Dipstick urine fo
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Proteinuria Is an important marker
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Investigations : Screening : Curr
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Diagnosis pre-renal Vs intrinsic re
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C/P of uraemia (uraemic syndrome) :
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Indication for Urgent Dialysis: Se
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II. Direct nephritogenic antibodies
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Pathology : Indications of renal b
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II. Adult polycystic kidney disease
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Nervous system Central nervous syst
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o Each hemisphere is formed of 2 la
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- The whit matter contains ascendin
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Pre-frontal area Anterior part of t
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Temporal lobe Auditory sensory area
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MRCP سؤال هام - It consists
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Muscle tone - This is spontaneous l
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The sensory system - Sensations in
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The cranial nerves I. Olfactory ner
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هام جدا فى االمتحان
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• Pathway of light reflex : - Sti
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N Muscles supplied Iry action 2ndry
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a) Ophthalmic branch : ‣ Pass in
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سؤال امتحان Trigeminal ne
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o Anhydrosis can determine the site
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• Facial nerve palsy : A. Causes
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سؤال امتحان : palsy Bell
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سؤال امتحان neuroma: Aco
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VIII. Vagus nerve - Mixed nerve car
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Supranuclear pathway : extend from
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• Abnormalities in conjugate gaze
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Blood supply of the brain - Brain i
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Middle cerebral artery (MCA) • Or
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48
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Circle of Willis - Both anterior ce
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Stroke (= cerebrovascular accident)
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Posterior cerebral artery Artery Ar
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• Management of stroke : (RCP gui
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2. ABCD2 score ≤ 3: Specialist a
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• Management : (mainly medical ,
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• Management : 1. Neurosurgical o
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Diseases of brain stem Lateral pont
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Diseases of spinal cord Transverse
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• Cardinal signs : Dissociated s
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Acute Confusional State - Is also k
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Dementia dfs adasd dhe • Def : -
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• Genetics: - Most cases are spor
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Creutzfeldt-Jakob disease(CJD) - It
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Motor neuron disease • Def : Is a
Page 788 and 789:
Duchenne`s muscle dystrophy - X-lin
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General features 1. Myotonic facies
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Features: The key feature is muscl
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Lambert-Eaton myasthenic syndrome
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Extrapyramidal disorders Extrapyram
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B. Role of cerebellum : 1. Ipsilate
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Tract Origin Inputs to origin Termi
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• Other features : Late complete
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Essential tremors : • Def : • C
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Progressive supranuclear palsy(PSP)
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Cerebellar diseases • Anatomy of
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7. Demyelinating disease : D.S , D.
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Friedrich`s ataxia Marie`s ataxia A
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Benign paroxysmal positional vertig
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سؤال امتحان Von Hippel-L
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Causes Examples Mainly sensory Main
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Mononeuropathy • Def : Neuropathy
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Tibial nerve (=posterior tibial ner
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هام جدا جدا Cutaneous ner
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Lower Back Pain (LBP) : - Is one of
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2. Intermediate group: ‣ Flexor d
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o Injury: at different levels cause
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• Treatment 1. Carpal injection (
Page 834 and 835:
Ulnar nerve o Origin : From the med
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May be worse when the elbow is rest
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130
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• Common examples for peripheral
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• Prognosis 20% suffer permanent
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Epilepsy • Def : - Recurrent (2 o
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- * Carbamazepine may actually exac
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Functional (Non-Epileptic) Seizures
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Demyelinating diseases Multible scl
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Neurofibromatosis - Is a geneticall
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• Def : inflammation of meninges.
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• Management of contacts Rifampi
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- Triptans should be given when the
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Paraneoplastic syndromes affecting
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Pharmacology of nervous system Ant
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156
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Anatomy of the eye - The eyeballs a
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Diseases of the retina I. Diabetic
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سؤال مهم جدا : if Urgent
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• Causes Multiple sclerosis DM
Page 874 and 875:
Diseases of the anterior segment of
Page 876 and 877:
Diseases of the pupil - The size of
Page 878 and 879:
سؤال مهم : Ptosis o Causes o
Page 880 and 881:
Diseases of the lens Cataracts - A
Page 882 and 883:
Diseases of the eyelids I. Blephari
Page 884 and 885:
• Management : Oral antiviral fo
Page 886 and 887:
General pharmacology Pharmacokineti
Page 888 and 889:
Drug administration & absorption :
Page 890 and 891:
- Ideal (lean) body weight (not tot
Page 892 and 893:
• Important example of drug metab
Page 894 and 895:
سؤال هام جدا : toxicity
Page 896 and 897:
Plot level against time on the reli
Page 898 and 899:
14
Page 900 and 901:
Cytochrome P-450 (CYP)enzyme family
Page 902 and 903:
Plasma half-life of the drug (t 1/2
Page 904 and 905:
Toxicology Salicylate Overdose Mix
Page 906 and 907:
TTT : Digibind (digoxin immune FAB)
Page 908 and 909:
1
Page 910 and 911:
• Clinical picture : Symptoms :
Page 912 and 913:
سؤال Tricyclic antidepressants
Page 914 and 915:
Selective serotonin reuptake inhibi
Page 916 and 917:
• Examples for MAOIs : - The Food
Page 918 and 919:
Bipolar disorder ( = manic depressi
Page 920 and 921:
Treatment of mixed affective state
Page 922 and 923:
- Features of acute lithium toxicit
Page 924 and 925:
Schizophrenia `splitting of mind`.
Page 926 and 927:
Anxiety disorders (anxiety neurosis
Page 928 and 929:
Post-traumatic stress disorder (PTS
Page 930 and 931:
Benzodiazepines - Benzodiazepines e
Page 932 and 933:
5. Dissociative disorder - Dissocia
Page 934 and 935:
2. Bulimia nervosa - Bulimia nervos
Page 936 and 937:
Rapid eye movement (REM) sleep beha
Page 938 and 939:
Divorced or widowed History of men
Page 941 and 942:
Respiratory Physiology • Main com
Page 943 and 944:
- Some conditions may cause an incr
Page 945 and 946:
Pulmonary function tests (PFTs) Lu
Page 947 and 948:
Tidal Volume (TV): - The volume of
Page 949 and 950:
B. Spirometry : - It`s the process
Page 951 and 952:
Interpretation of PFTs : (all resp.
Page 953 and 954:
More simplified&summarized
Page 955 and 956:
Oxygen dissociation curve - The oxy
Page 957 and 958:
‣ Signs : Patients with acute ast
Page 959 and 960:
Management of BA in adults : A) Man
Page 962 and 963:
Chronic obstructive pulmonary disea
Page 964 and 965:
Other signs : 1. Cyanosis (in chron
Page 966 and 967:
Management of acute exacerbation in
Page 968 and 969:
6. Nocturnal NIV (BiPAP) - Used in
Page 970 and 971:
Sleep apnoea - i.e Periods of compl
Page 972 and 973:
Bronchiectasis - Bronchiectasis des
Page 974 and 975:
7- Investigations for the cause : -
Page 976 and 977:
Investigations : 1. CF phenotyping.
Page 978 and 979:
Investigations : 2012 NICE guidelin
Page 980 and 981:
3. V/Q scan Sensitivity = 98%; spe
Page 982 and 983:
Pneumonia - Pneumonitis is an infla
Page 984 and 985:
Characteristic features of pneumoco
Page 986 and 987:
Legionella pneumonia - Legionnaire'
Page 988 and 989:
Aspergillus and the lung - Aspergil
Page 990 and 991:
Invasive (=angio-invasive) pulmonar
Page 992 and 993:
Complicated CWP (progressive massiv
Page 994 and 995:
• Prognosis : Poor (average life
Page 996 and 997:
• Staging of lung cancer :
Page 998 and 999:
Types of lung cancer : A) Small (oa
Page 1000 and 1001:
أهم مافي الموضوع : su
Page 1002 and 1003:
• Basics Acute(adult) respiratory
Page 1004 and 1005:
Sarcoidosis - Sarcoidosis is multis
Page 1006 and 1007:
سؤال هام : diagnosis • Dif
Page 1008 and 1009:
• Investigations [British Thoraci
Page 1010 and 1011:
• Risk factors of spontaneous pne
Page 1012 and 1013:
أهم مافي الموضوع : 20
Page 1014 and 1015:
Smoking cessation - Nicotine is a s
Page 1016 and 1017:
Q4 : Which of the following is NOT
Page 1018:
- A normal or elevated pCO2 in an a
Page 1021 and 1022:
II. Arthrocentesis & synovial fluid
Page 1023 and 1024:
• Investigations : 1) Plain x-ray
Page 1025 and 1026:
• Differential diagnosis is broad
Page 1027 and 1028:
& granulation tissue pannus formati
Page 1029 and 1030:
Extra-articular manifistations Ski
Page 1031 and 1032:
• Management of rheumatoid arthri
Page 1033 and 1034:
• Poor prognostic features of RA
Page 1035 and 1036:
• Investigations : 1) ESR & CRP :
Page 1037 and 1038:
• Investigations : X-ray : - Pen
Page 1039 and 1040:
• Management Symptomatic: analge
Page 1041 and 1042:
Septic arthritis Joint aspiration i
Page 1043 and 1044:
• Clinical picture: - A number of
Page 1045 and 1046:
أهم مافي الموضوع في
Page 1047 and 1048:
• Features: Knee, wrist and shou
Page 1049 and 1050:
• Other features Proximal muscle
Page 1051 and 1052:
تجميعة مهمة جدا Diseas
Page 1053 and 1054:
Elbow Pain: - The table below detai
Page 1055 and 1056:
Adhesive capsulitis (frozen shoulde
Page 1057 and 1058:
C. Ottawa rules for knee injury : -
Page 1059 and 1060:
B. Skin manifistations : 1. Malar f
Page 1061 and 1062:
• Monitoring ESR & CRP: - High E
Page 1063 and 1064:
SLE and pregnancy : - Unlike many a
Page 1065 and 1066:
Limited cutaneous systemic sclerosi
Page 1067 and 1068:
Raynaud's phenomena • Def : - Is
Page 1069 and 1070:
Systemic vasculitis • Def : - Gro
Page 1071 and 1072:
• Clinical features : A. Giant ce
Page 1073 and 1074:
Medium sized vasculitis Polyarterit
Page 1075 and 1076:
Churg-Strauss syndrome - Is an ANCA
Page 1077 and 1078:
- It`s an immune complex mediated A
Page 1079 and 1080:
Chronic fatigue syndrome - Diagnose
Page 1081 and 1082:
Methotrexate : Drugs used in rheuma
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DR Medhat MRCP

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