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CLINICAL LAB SCIENEC

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CHAPTER 6: INTRODUCTION TO INFECTION CONTROL 119

might have eclipsed anything experienced previously, including that of bubonic

plague in the 15th century.

Most larger hospitals have comprehensive microbiology departments that are

able to identify and provide information for the initiation of adequate treatments

for a number of virulent pathogens. The five basic categories of microorganisms

are bacterial, viral, parasitic, rickettsial (a specialized bacterium of increasing

prevalence) , and fungal organisms. There are a few others, including subviral

particles called prions, (the source of the well-publicized “mad cow disease”). In

the case of rickettsial infections, the causative organism is usually transmitted by

a tick vector or carrier. Newer and less well-defined organisms other than these

five categories will doubtless be discovered.

The administration of antibiotics that are specific for only certain bacteria

is of little value in treating many bacterial organisms. Some broad-spectrum

antibiotics will indiscriminately destroy most bacterial strains, including normal

flora. This presents an opportunity for potentially harmful organisms to

take the place of the normal flora. Also, most respiratory infections such as the

common cold are caused by viruses against which antibiotics will do nothing

or may even exacerbate the growth of the virus. The wholesale prescribing of

antibiotics without identifying the presence of a pathogen has led to the rise

of many bacteria that are resistant to almost every antibiotic currently in use.

Many infections that are difficult to treat arise in patients who are hospitalized

and have contract ed an antibiotic-resistant organisms while in the facility.

Major sources of hospital-acquired infections (termed nosocomial infections

and iatrogenic infections) are caused by organisms that gain entry into and

colonize the body through the introduction of medical devices used for various

treatments.

With the proliferation of new medical procedures, some of an elective nature,

the rise in infections by resistant strains may cause a local epidemic within a

health care facility. In a number of cases, the Infection Control Committee will

trace certain strains of bacteria to a single physician, to instruments, or to other

health care workers. Protecting oneself against these dangerous organisms is

paramount, and most disease prevention efforts are focused toward teaching

the health care worker protection against a whole host of organisms. Infection

by bloodborne and airborne pathogens other than HIV, HBV , and TB, as well

as by environmental organisms, must be prevented through the use of precautions

designed to protect both the worker and the patient. Economy and efficiency

dictate that effective and conscientious efforts be pursued to avoid either

the health care professional, the student, or a patient from being infected. These

efforts will pay dividends in lowering our health care costs as a nation, as well

as preventing needless suffering and inconvenience.

To protect workers and employees against infection by HIV, HBV, or TB, the

infection control program of each medical facility and each educational institution

classifies job positions by potential for exposure. These levels of potential

risk range from Category I through Category III, with Category I including

workers at most risk, and Category III representing health care workers with

little risk of exposure. Although literally thousands of organisms are capable

of causing serious infections in humans, only two major organisms associated

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