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12.5.2.30 DHS rekommandationer for KMT 2011.pdf - e-Dok

12.5.2.30 DHS rekommandationer for KMT 2011.pdf - e-Dok

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allogen transplantation kan anvendes ved alder over 55 år.<br />

Primær resistent ALL (induction failure) eller ALL i relaps<br />

Der er ikke indikation <strong>for</strong> allogen HCT.<br />

Referencer vedrørende HCT af ALL hos voksne<br />

Risikofaktorer<br />

Hoelzer, D., Thiel, E., Loffler, H., Buchner, T., Ganser, A. et al (1988). Prognostic factors in a multicenter study<br />

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Gleissner B, Goekbuget N, Rieder H et al (2005). CD10- pre-B acute lymphoblastic leukaemia (ALL) is a distinct<br />

high-risk subgroup of adult ALL associated with a high frequency of MLL aberrations: results of the German<br />

Multicenter Trials <strong>for</strong> Adult ALL (GMALL). Blood, 106, 4054-4056.<br />

Czuczman M, Dodge R, Carleton C, Stewart RS et al (1999). Value of immunephenotype in intensively treated<br />

adult acute lymphoblastic leukaemia: Cancer and Leukemia Group B study 8364.Blood, 93, 3931-3939.<br />

Ferrando A, Neuberg DS, Dodge RK, Paiette E et al (2004). Prognostic importance of TLX1 (HOX11) oncogen<br />

expression in adults with T-cell acute lymphoblasic leukaemia. Lancet, 363, 535-536.<br />

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in adult acute lymphoblastic leukemia. Blood , 91, 3995-4019.<br />

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ute lymphoblastic leukaemia: The Cancer and Leukemia Group B experience. Blood, 93,3983-3993.<br />

Charrin C, Thomas X, Ffrench M, Le Q-H et al (2004). A report from the LALA-94 and LALA-SA groups on<br />

hypodiploidi with 30-39 chromosomes and near-triploidi: 2 possible expressions of a sole entity conferring poor<br />

prognosis in adult acute lymphoblastic leukaemia (ALL). Blood,104, 2444-2451.<br />

Harrison C, Moorman A, Broadfield Z, Cheung K et al (2004). Three distinct subgroups of hypodiploidi in acyte<br />

lymphoblastic leukaemia. Brit J Haematol , 125, 552-559.<br />

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leukaemia at diagnosis: results from the international ALL trial MRC UKALL XII/ECOG E 2993. Blood, 108, 465-<br />

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lymphoblastic leukaemia(ALL): analysis of cytogenetic data from patients treated on the Medican Research<br />

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novo precursor B-lineage acute lymphoblastic leukaemia. Blood, prepublished online 14 Aug 2008.<br />

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