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OP 123<br />

Title<br />

SEGMENTATION OF TRAbECuLAR JAW bONE ON CbCT DATASETS<br />

Authors<br />

O. NACKAERTS 1 , M. DEPyPERE 2 , G. zHANG 3 , F. MAES 2 , R. JACObS 1 , SEDENTEXCT 4<br />

Affiliations<br />

1 Oral Imaging Centre, KU Leuven, Leuven, BELGIUM, 2 ESAT, KU Leuven, Leuven, BELGIUM, 3<br />

Radiology, KU Leuven, Leuven, BELGIUM, 4 www.sedentexCT.eu, Manchester, UNITED KINGDOM<br />

Body<br />

Aims<br />

The aim of this research w<strong>as</strong> to <strong>as</strong>sess the accuracy of segmentation procedures on CBCT images<br />

with µCT images <strong>as</strong> the reference standard.<br />

Method<br />

Four human formalin-fixed jaws <strong>including</strong> soft tissues were scanned with 9 different CBCT<br />

devices with a µCT device.<br />

In CT-analyser, 2 regions of interest for each jaw were chosen. The regions of interest were<br />

segmented for each CBCT scanner, first with global, then with adaptive thresholding. Finally,<br />

one observer performed the thresholding manually.<br />

The optimal threshold w<strong>as</strong> determined for each scanner with ROC analysis and compared to<br />

manual thresholding. The reference standard for ROC analysis w<strong>as</strong> the (manual) thresholding<br />

on the µCT scans.<br />

Results<br />

Adaptive thresholding yielded much higher accuracy levels than global thresholding. Moreover,<br />

adaptive thresholding w<strong>as</strong> less sensitive to shifts in thresholding. The device cl<strong>as</strong>sification<br />

b<strong>as</strong>ed on best accuracy w<strong>as</strong> comparable to intuitive image quality <strong>as</strong>sessment.<br />

With manual thresholding, a consistent underestimation of bone volume occurred. This w<strong>as</strong><br />

most probably due to the borders of the regions of interest, w<strong>here</strong> more opaque are<strong>as</strong> are<br />

visible.<br />

Conclusion<br />

Adaptive thresholding is an e<strong>as</strong>y way of rendering bone segmentation on CBCT more stable and<br />

of a higher quality than can be done with global thresholding. With manual thresholding, the<br />

focus should be on the central part of the regions of interest. Follow-up research will aim at<br />

defining a valid way for automatic optimal threshold detection.<br />

Keywords<br />

bone, µCT, segmentation<br />

100

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