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P 95
Title
EFFECT OF LOW-INTENSITy PuLSED uLTRASOuND ON HEALING OF MANDIbuLAR
bONE DEFECTS
Authors
P. bRONOOSH 1 , N. TANIDE 2
Affiliations
1 shiraz university of medical sciences department of oral radiology, Shiraz, IRAN, 2 shiraz
university of medical sciences department of animal lab, Shiraz, IRAN
Body
Objective: Pulsed ultrasonic waves have been shown to accelerate fracture healing of the long
bones. The aim of this study was to evaluate the effect of low-intensity pulsed ultrasound
(LIPU) on healing of mandibular bone defects in rabbits.
Methods: 45 skeletally mature male Dutch rabbits were divided in three groups. All animals
underwent anesthesia and through a submandibular approach, a 5 mm bone defect was prepared
medial to mental foramen in one side. First group of the animals received daily 1MHz
ultrasound treatment, 10 min/day, for 28 days. Second group received 3MHz ultrasound with
same protocol. Animals in the control group received sham application. All of the animals
were sacrificed on postoperative day 29. Bone mineral density(BMD), stereology and histologic
examinations were performed on the harvested hemimandibles. The data were statistically
analyzed.
Results: BMD revealed improvement in the bone density of the healing bone in the LIPUtreated
group. This was supported by histologic and stereologic findings.The results were not
different between 1and 3MHz groups.
Conclusions: Results of this study suggest that LIPU improves the bone healing of mandibular
defects in rabbits.
Further research to evaluate the effect of LIPU on human jaw bone healing is recommended.
Keywords
ultrasound,mandible,defect
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