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P 53
Title
MuLTIPLE bROWN TuMORS OF THE JAWS: REPORT OF TWO CASES
Authors
A. LEITE 1 , F.R. bARRA 2 , R. FOCKINK 2 , A.P. PAuLA 3 , E.N. SILVA GuERRA 1 , N.S. MELO 1
Affiliations
1 Faculty of Health Sciences, Department of Dentistry, University of Brasília, Brasília, BRA-
ZIL, 2 Medical Radiology, University Hospital of Brasília, Brasília, BRAZIL, 3 Faculty of Health
Sciences, University of Brasília, Brasília, BRAZIL
Body
Objectives: Primary hyperparathyroidism (HPT) is characterized by hypersecretion of parathyroid
hormone, generally resulting from adenomas. Secondary HPT is commonly seen in chronic
renal failure patients associated with calcium or vitamin D deficiency. Brown tumors are rare
giant-cell lesions resulting from abnormal bone metabolism in HPT. These tumors are more
common in long bones, but rarely appear in jaws. The objective of this study was to report two
cases of brown tumors of the jaws associated with primary and secondary HPT.
Methods: Two patients were referred to the University Hospital of Brasilia with complain of
swellings on the upper and lower jaws. Clinical, imaging and biochemical examinations were
performed.
Results: The first patient was a 31-year-old female complaining of swelling on the upper jaw.
Panoramic radiograph revealed five radiolucent areas (3 in the maxilla and 2 in the mandible).
Anterior upper teeth presented root resorption. Computed tomography (CT) showed one
lesion causing expansion of the buccal cortex, and one lesion penetrating the left maxillary
sinus. Hypercalcemia and an abnormal level of parathyroid hormone (PTH) were detected. A
single-gland parathyroid adenoma was identified. The second patient was a 33-year-old female
presenting a mandibular lesion. She was a chronic renal failure patient on haemodialysis.
Panoramic radiograph showed 2 radiolucent areas in the mandible, causing displacement of
the anterior teeth. CT and magnetic resonance imaging demonstrated a huge expansion of the
buccal cortex and perforation of the lingual cortex.
Conclusions: Oral and maxillofacial radiologists may identify bony tumors associated with
primary and secondary HPT.
Keywords
Hyperparathyroidism,Multislice computed tomography,Craniofacial abnormalities
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