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P 80
Title
PRIMARy LEIOMyOSARCOMA OF MAXILLA; A CASE REPORT
Authors
S. FARDISI 1 , S. AMANPOuR 2 , P. bRONOOSH 3
Affiliations
1 Shiraz university of medical sciences department of oral surgery, shiraz, IRAN, 2 Shiraz
university of medical sciences department of oral pathology, shiraz, IRAN, 3 Shiraz university
of medical sciences department of oral radiology, shiraz, IRAN
Body
INTRODUCTION:
leiomyosarcoma is a malignant neoplasm of smooth muscle origin and accounts for about 7%
of all soft-tissue sarcomas. Most of these tumors occur in the uterus, gastrointestinal tract
and retroperitoneum. Few leiomyosarcomas occur in the oral cavity; leiomyosarcoma of the
jaw bones is extremely rare. We describe a rare case of maxillary leiomyosarcoma with a special
emphasis on radiographic features and diagnosis.
Case report
A 36-year-old man was referred by dentist to our clinic, because of swelling and tooth mobility
in anterior of maxilla. Oral examination revealed a tender swelling extending from the alveolar
process of left second premolar to right canine tooth. The involved teeth were mobile. Panoramic
radiography revealed an ill-defined radiolucency with bone erosion and resorption of
the lamina dura. Computed tomography scans depicted a space-occupying mass which caused
bony destruction of left maxillary alveoli and anterior part of hard palate. Bone erosion was
also seen in anterior medial wall of left maxillary antrum. Incisional biopsy was done and
microscopic examination showed a neoplasm composed of spindle-shaped cells with fascicular
pattern and smooth muscle differentiation. Immunohistochemistry was carried out and based
on positivity of tumor cells for vimentin, desmin and smooth muscle actin the diagnosis of
leiomyosarcoma was done for this lesion. The lesion was excised through maxillectomy and
post operative radiotherapy was recommended.
Conclusion:
Although primary leiomyosarcoma of the jaws is rare, it should be consider in differential
diagnosis of central malignant lesions.
Keywords
Leiomyosarcoma,primary,maxilla
POSTerS
195