LVR-Klinikum Düsseldorf Hospital of the Heinrich-Heine University ...
LVR-Klinikum Düsseldorf Hospital of the Heinrich-Heine University ...
LVR-Klinikum Düsseldorf Hospital of the Heinrich-Heine University ...
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<strong>LVR</strong>-KLINIKUM DÜsseLDORF – hOsPITaL OF The heINRIch-heINe UNIVeRsITY DÜsseLDORF<br />
3.1 Department <strong>of</strong> Psychiatry and Psycho<strong>the</strong>rapy<br />
3.1.1 Research Networks<br />
During <strong>the</strong> reporting period, <strong>the</strong> <strong>LVR</strong>-<strong>Klinikum</strong> <strong>Düsseldorf</strong><br />
was a member or at <strong>the</strong> head <strong>of</strong> several countrywide or<br />
regional research networks. Worthy <strong>of</strong> specific mention here<br />
are <strong>the</strong> “Competence Networks in Medicine” which, since<br />
1999, have been funded by <strong>the</strong> German Federal Ministry for<br />
Education and Research (FMER) to improve cooperation<br />
between <strong>the</strong> leading research institutions in specific research<br />
areas (horizontal networking) and those providing routine<br />
care (vertical networking) for individual clinical pictures<br />
across all fields <strong>of</strong> medicine. The programme is designed<br />
to make a contribution to improving <strong>the</strong> treatment <strong>of</strong> people<br />
with clinical pictures characterised by high morbidity and/or<br />
mortality rates. The Competence Network on Schizophrenia<br />
was one <strong>of</strong> <strong>the</strong> (initially nine, now eighteen) federally-funded,<br />
countrywide competence networks. The network was<br />
essentially <strong>the</strong> brainchild <strong>of</strong> <strong>the</strong> Department <strong>of</strong> Psychiatry<br />
and Psycho<strong>the</strong>rapy <strong>of</strong> <strong>the</strong> <strong>Heinrich</strong>-<strong>Heine</strong> <strong>University</strong>, <strong>LVR</strong>-<br />
<strong>Klinikum</strong> <strong>Düsseldorf</strong>, toge<strong>the</strong>r with <strong>the</strong> Department <strong>of</strong><br />
Psychiatry and Psycho<strong>the</strong>rapy <strong>of</strong> <strong>the</strong> Ludwig-Maximilian<br />
<strong>University</strong>, Munich (H.-J. Möller) and, since its start in 1999,<br />
has been coordinated by <strong>the</strong> Network Headquarters at <strong>the</strong><br />
Department <strong>of</strong> Psychiatry and Psycho<strong>the</strong>rapy, <strong>LVR</strong>-<strong>Klinikum</strong>.<br />
The spokesperson for <strong>the</strong> competence network is W. Gaebel.<br />
In addition, <strong>the</strong> <strong>LVR</strong>-<strong>Klinikum</strong> <strong>Düsseldorf</strong> has also been linked<br />
with research projects within <strong>the</strong> Competence Networks on<br />
Depression and Suicidality and has participated in projects <strong>of</strong><br />
<strong>the</strong> Competence Network on Dementia. In close collaboration<br />
with <strong>the</strong> Competence Network programme, <strong>the</strong> FMER has<br />
set up o<strong>the</strong>r associated research funding programmes, in<br />
which <strong>the</strong> Department <strong>of</strong> Psychiatry and Psycho<strong>the</strong>rapy<br />
takes part. This allowed, for instance, corresponding brain<br />
banks from different Competence Networks to be pooled<br />
into a cross-illness brain bank that can be used as a<br />
reference centre for CNS disorders (BrainNet), with which<br />
<strong>the</strong> Department <strong>of</strong> Psychiatry and Psycho<strong>the</strong>rapy is linked<br />
as an Associate Satellite Centre. In order to work on joint<br />
legal, organisational and technical solutions to problems<br />
simultaneously facing a number <strong>of</strong> research associations, <strong>the</strong><br />
FMER set up <strong>the</strong> Telematics Platform for Medical Research<br />
Networks (TMF e. V.), which has since taken <strong>the</strong> legal form<br />
<strong>of</strong> a registered non-pr<strong>of</strong>it association. The Competence<br />
Network on Schizophrenia is, amongst o<strong>the</strong>rs, a member <strong>of</strong><br />
this “umbrella association” <strong>of</strong> medical research networks and<br />
toge<strong>the</strong>r with o<strong>the</strong>r neuropsychiatric competence networks<br />
has attracted project funding for <strong>the</strong> creation <strong>of</strong> interfaces<br />
for exchanging data between clinical documentation systems<br />
58<br />
from <strong>the</strong> TMF. Finally, when <strong>the</strong> second funding period for<br />
<strong>the</strong> Competence Network on Schizophrenia ended in 2005, a<br />
countrywide research network for “Psycho<strong>the</strong>rapy in Positive<br />
Symptoms” (POSITIVE) was set up, which was conceived and<br />
initiated by <strong>the</strong> Tübingen <strong>University</strong> <strong>Hospital</strong> (S. Klingberg<br />
and G. Buchkremer) in close collaboration with cooperation<br />
partners from <strong>the</strong> Competence Network on Schizophrenia,<br />
including <strong>the</strong> network headquarters, and which has been<br />
coordinated by colleagues from Tübingen since its approval in<br />
2006. The Department <strong>of</strong> Psychiatry and Psycho<strong>the</strong>rapy is an<br />
active participant in almost all <strong>of</strong> <strong>the</strong>se research association<br />
projects. In <strong>the</strong> area <strong>of</strong> dependence and basic research, <strong>the</strong><br />
DFG Priority Programme 1226 “Nicotine: Molecular and<br />
Physiological Effects on <strong>the</strong> Central Nervous System” has<br />
been coordinated since 2006 at <strong>the</strong> <strong>LVR</strong>-<strong>Klinikum</strong> <strong>Düsseldorf</strong><br />
with G. Winterer as <strong>the</strong> spokesperson. He initiated <strong>the</strong><br />
programme, has contributed various projects and has<br />
participated in o<strong>the</strong>r projects. The objective <strong>of</strong> <strong>the</strong>se partially<br />
multi-site projects was <strong>the</strong> elucidation <strong>of</strong> <strong>the</strong> moleculargenetic<br />
principles <strong>of</strong> <strong>the</strong> effects <strong>of</strong> nicotine and nicotine<br />
dependence, as well as <strong>the</strong> neurobiological and clinical<br />
effects <strong>of</strong> nicotine. Moreover, <strong>the</strong> <strong>LVR</strong>-<strong>Klinikum</strong> <strong>Düsseldorf</strong><br />
was part <strong>of</strong> <strong>the</strong> Dependence Research Network North Rhine-<br />
Westphalia, initially conceived and managed by <strong>the</strong> <strong>LVR</strong>-<br />
<strong>Klinikum</strong> Essen. The <strong>LVR</strong>-<strong>Klinikum</strong> <strong>Düsseldorf</strong> contributed<br />
an own multi-centre project to this network and assumed its<br />
leadership in 2006.<br />
3.1.1.1 Competence Network on Schizophrenia (FMER)<br />
Spokesperson: W. Gaebel<br />
Network Headquarters: W. Wölwer, V. Toeller (from 2005),<br />
L. Freimüller (from 2008), S.-K. Schul<strong>the</strong>is (2005–2007),<br />
T. Ferrari (2003–2006), A. Weßling (until 2005)<br />
The Competence Network’s objectives<br />
The main concern <strong>of</strong> <strong>the</strong> Competence Network on<br />
Schizophrenia is <strong>the</strong> creation <strong>of</strong> scientific prerequisites for<br />
<strong>the</strong> optimisation <strong>of</strong> <strong>the</strong> prevention, acute and long-term<br />
treatment, and <strong>the</strong> rehabilitation <strong>of</strong> schizophrenic disorders.<br />
Contributions will be made to <strong>the</strong> following concrete<br />
objectives by means <strong>of</strong> practice-related and networked<br />
research projects and measures for health education: