LVR-Klinikum Düsseldorf Hospital of the Heinrich-Heine University ...
LVR-Klinikum Düsseldorf Hospital of the Heinrich-Heine University ...
LVR-Klinikum Düsseldorf Hospital of the Heinrich-Heine University ...
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<strong>LVR</strong>-KLINIKUM DÜsseLDORF – hOsPITaL OF The heINRIch-heINe UNIVeRsITY DÜsseLDORF<br />
Astra Zeneca, Bayer Vital, Hexal, Novartis, Neuraxpharm<br />
and Pfizer).<br />
Local research facilities participating in<br />
<strong>the</strong> Competence Network<br />
The Department <strong>of</strong> Psychiatry and Psycho<strong>the</strong>rapy <strong>of</strong> <strong>the</strong><br />
<strong>Heinrich</strong>-<strong>Heine</strong> <strong>University</strong> <strong>Düsseldorf</strong>, as <strong>the</strong> primary<br />
applicant <strong>of</strong> <strong>the</strong> Competence Network, is actively involved<br />
in a total <strong>of</strong> 27 projects, 19 <strong>of</strong> which have mainly been<br />
conceived by one <strong>of</strong> <strong>the</strong> Department´s various research<br />
laboratories and research groups, which also appointed <strong>the</strong><br />
respective project director <strong>of</strong> <strong>the</strong>se studies. In addition, <strong>the</strong><br />
Department´s research units are associated with eight o<strong>the</strong>r<br />
projects as <strong>the</strong> cooperation partner <strong>of</strong> o<strong>the</strong>r institutions<br />
(Table 3). A differentiated description <strong>of</strong> <strong>the</strong>se projects as<br />
well as <strong>the</strong> current type <strong>of</strong> participation can be found in <strong>the</strong><br />
respective report chapters by <strong>the</strong> research laboratories and<br />
groups in this volume.<br />
3.1.1.2 Competence Network on Depression<br />
62<br />
and Suicidality (FMER)<br />
Centre directors: W. Gaebel, F. Schneider (until 2004)<br />
The main objective <strong>of</strong> <strong>the</strong> Competence Network on<br />
Depression and Suicidality is to contribute to improving<br />
<strong>the</strong> prevention, diagnosis and treatment <strong>of</strong> depression<br />
and suicidality. This is achieved through <strong>the</strong> networking <strong>of</strong><br />
research, care, self-management, cost-carriers and patient<br />
representatives within <strong>the</strong> context <strong>of</strong> an extensive range <strong>of</strong><br />
application-oriented research patterns, as well as informing<br />
<strong>the</strong> public and persons with depression or suicidality. In<br />
more detail, this guiding idea is put into practice by means <strong>of</strong><br />
<strong>the</strong> following sub-goals:<br />
s Suicide prevention through <strong>the</strong> continuous training<br />
<strong>of</strong> general practitioners and educating persons with<br />
depression or suicidality and <strong>the</strong> public.<br />
s Expanding existing knowledge regarding <strong>the</strong> biological<br />
causes <strong>of</strong> <strong>the</strong> disorder and <strong>the</strong> social framework<br />
conditions<br />
s Improving <strong>the</strong> treatment <strong>of</strong> mild and sub-diagnostic<br />
depressive disorders.<br />
s Improving <strong>the</strong> treatment <strong>of</strong> relapsing brief depressive<br />
disorders and preventing chronification.<br />
s Improving <strong>the</strong> quality <strong>of</strong> diagnosis and treatment<br />
through <strong>the</strong> use <strong>of</strong> guidelines.<br />
s Evaluating quality-related measures through<br />
comparative health economic analyses.<br />
s Developing and testing guideline-oriented<br />
compensation systems.<br />
s Investigating <strong>the</strong> biological mechanisms <strong>of</strong><br />
antidepressants.<br />
s Improving pharmaco<strong>the</strong>rapy by redetermining<br />
intervention points.<br />
s Basic research for <strong>the</strong> development <strong>of</strong> new<br />
medications.<br />
s Investigating genetic predispositions for affective<br />
disorders.<br />
s Investigating <strong>the</strong> relationship between genetic factors<br />
and medication-related treatment processes.<br />
s Investigating <strong>the</strong> conditions <strong>of</strong> chronification and<br />
treatment resistance; developing new intervention<br />
strategies.<br />
s Informing <strong>the</strong> public, persons with depression or<br />
suicidality, and <strong>the</strong>ir relatives through targeted<br />
knowledge transfer.<br />
The structures and topics <strong>of</strong> <strong>the</strong> Competence Network<br />
The Competence Network on Depression and Suicidality is<br />
subdivided into six projects (PP), each <strong>of</strong> which is divided<br />
into various sub-projects (SP). In accordance with <strong>the</strong><br />
Competence Network’s comprehensive target setting,<br />
<strong>the</strong> research associated with PP 1–3 was <strong>the</strong>matically<br />
concentrated on optimising and assuring adequate<br />
healthcare procedures in <strong>of</strong>fice- and hospital-based<br />
treatment settings, as well as educating <strong>the</strong> public and<br />
persons with depression or suicidality, whereas <strong>the</strong> SP<br />
4–6 projects were concerned with investigating <strong>the</strong> genetic<br />
and brain-biological causes <strong>of</strong> depressive illnesses<br />
and, accordingly, should lead to ideas for treatment and<br />
prediction (cf. Table 4).<br />
Partners involved in <strong>the</strong> Competence<br />
Network across Germany<br />
Across Germany, <strong>the</strong> Competence Network on Depression<br />
and Suicidality includes 18 scientific institutions, several<br />
psychiatric departments (university, state, regional and<br />
specialist hospitals) as well as psychiatric and general<br />
medicine practice networks, self-help groups (Horizonte,<br />
DASH and MASH), <strong>the</strong> Drug Commission <strong>of</strong> <strong>the</strong> German<br />
Medical Association and numerous State Associations <strong>of</strong><br />
Statutory Health Insurance Physicians. The Competence<br />
Network’s work is supported by specialist associations<br />
(such as <strong>the</strong> German Association <strong>of</strong> Psychiatry and<br />
Psycho<strong>the</strong>rapy, DGPPN), pr<strong>of</strong>essional associations and <strong>the</strong><br />
health funds’ umbrella associations (Central Association <strong>of</strong><br />
Health Insurance Funds [“GKV-Spitzenverband”in German];<br />
Federation <strong>of</strong> Alternative Health Insurance Funds [“Verband