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LVR-Klinikum Düsseldorf Hospital of the Heinrich-Heine University ...

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<strong>LVR</strong>-KLINIKUM DÜsseLDORF – hOsPITaL OF The heINRIch-heINe UNIVeRsITY DÜsseLDORF<br />

Astra Zeneca, Bayer Vital, Hexal, Novartis, Neuraxpharm<br />

and Pfizer).<br />

Local research facilities participating in<br />

<strong>the</strong> Competence Network<br />

The Department <strong>of</strong> Psychiatry and Psycho<strong>the</strong>rapy <strong>of</strong> <strong>the</strong><br />

<strong>Heinrich</strong>-<strong>Heine</strong> <strong>University</strong> <strong>Düsseldorf</strong>, as <strong>the</strong> primary<br />

applicant <strong>of</strong> <strong>the</strong> Competence Network, is actively involved<br />

in a total <strong>of</strong> 27 projects, 19 <strong>of</strong> which have mainly been<br />

conceived by one <strong>of</strong> <strong>the</strong> Department´s various research<br />

laboratories and research groups, which also appointed <strong>the</strong><br />

respective project director <strong>of</strong> <strong>the</strong>se studies. In addition, <strong>the</strong><br />

Department´s research units are associated with eight o<strong>the</strong>r<br />

projects as <strong>the</strong> cooperation partner <strong>of</strong> o<strong>the</strong>r institutions<br />

(Table 3). A differentiated description <strong>of</strong> <strong>the</strong>se projects as<br />

well as <strong>the</strong> current type <strong>of</strong> participation can be found in <strong>the</strong><br />

respective report chapters by <strong>the</strong> research laboratories and<br />

groups in this volume.<br />

3.1.1.2 Competence Network on Depression<br />

62<br />

and Suicidality (FMER)<br />

Centre directors: W. Gaebel, F. Schneider (until 2004)<br />

The main objective <strong>of</strong> <strong>the</strong> Competence Network on<br />

Depression and Suicidality is to contribute to improving<br />

<strong>the</strong> prevention, diagnosis and treatment <strong>of</strong> depression<br />

and suicidality. This is achieved through <strong>the</strong> networking <strong>of</strong><br />

research, care, self-management, cost-carriers and patient<br />

representatives within <strong>the</strong> context <strong>of</strong> an extensive range <strong>of</strong><br />

application-oriented research patterns, as well as informing<br />

<strong>the</strong> public and persons with depression or suicidality. In<br />

more detail, this guiding idea is put into practice by means <strong>of</strong><br />

<strong>the</strong> following sub-goals:<br />

s Suicide prevention through <strong>the</strong> continuous training<br />

<strong>of</strong> general practitioners and educating persons with<br />

depression or suicidality and <strong>the</strong> public.<br />

s Expanding existing knowledge regarding <strong>the</strong> biological<br />

causes <strong>of</strong> <strong>the</strong> disorder and <strong>the</strong> social framework<br />

conditions<br />

s Improving <strong>the</strong> treatment <strong>of</strong> mild and sub-diagnostic<br />

depressive disorders.<br />

s Improving <strong>the</strong> treatment <strong>of</strong> relapsing brief depressive<br />

disorders and preventing chronification.<br />

s Improving <strong>the</strong> quality <strong>of</strong> diagnosis and treatment<br />

through <strong>the</strong> use <strong>of</strong> guidelines.<br />

s Evaluating quality-related measures through<br />

comparative health economic analyses.<br />

s Developing and testing guideline-oriented<br />

compensation systems.<br />

s Investigating <strong>the</strong> biological mechanisms <strong>of</strong><br />

antidepressants.<br />

s Improving pharmaco<strong>the</strong>rapy by redetermining<br />

intervention points.<br />

s Basic research for <strong>the</strong> development <strong>of</strong> new<br />

medications.<br />

s Investigating genetic predispositions for affective<br />

disorders.<br />

s Investigating <strong>the</strong> relationship between genetic factors<br />

and medication-related treatment processes.<br />

s Investigating <strong>the</strong> conditions <strong>of</strong> chronification and<br />

treatment resistance; developing new intervention<br />

strategies.<br />

s Informing <strong>the</strong> public, persons with depression or<br />

suicidality, and <strong>the</strong>ir relatives through targeted<br />

knowledge transfer.<br />

The structures and topics <strong>of</strong> <strong>the</strong> Competence Network<br />

The Competence Network on Depression and Suicidality is<br />

subdivided into six projects (PP), each <strong>of</strong> which is divided<br />

into various sub-projects (SP). In accordance with <strong>the</strong><br />

Competence Network’s comprehensive target setting,<br />

<strong>the</strong> research associated with PP 1–3 was <strong>the</strong>matically<br />

concentrated on optimising and assuring adequate<br />

healthcare procedures in <strong>of</strong>fice- and hospital-based<br />

treatment settings, as well as educating <strong>the</strong> public and<br />

persons with depression or suicidality, whereas <strong>the</strong> SP<br />

4–6 projects were concerned with investigating <strong>the</strong> genetic<br />

and brain-biological causes <strong>of</strong> depressive illnesses<br />

and, accordingly, should lead to ideas for treatment and<br />

prediction (cf. Table 4).<br />

Partners involved in <strong>the</strong> Competence<br />

Network across Germany<br />

Across Germany, <strong>the</strong> Competence Network on Depression<br />

and Suicidality includes 18 scientific institutions, several<br />

psychiatric departments (university, state, regional and<br />

specialist hospitals) as well as psychiatric and general<br />

medicine practice networks, self-help groups (Horizonte,<br />

DASH and MASH), <strong>the</strong> Drug Commission <strong>of</strong> <strong>the</strong> German<br />

Medical Association and numerous State Associations <strong>of</strong><br />

Statutory Health Insurance Physicians. The Competence<br />

Network’s work is supported by specialist associations<br />

(such as <strong>the</strong> German Association <strong>of</strong> Psychiatry and<br />

Psycho<strong>the</strong>rapy, DGPPN), pr<strong>of</strong>essional associations and <strong>the</strong><br />

health funds’ umbrella associations (Central Association <strong>of</strong><br />

Health Insurance Funds [“GKV-Spitzenverband”in German];<br />

Federation <strong>of</strong> Alternative Health Insurance Funds [“Verband

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