LVR-Klinikum Düsseldorf Hospital of the Heinrich-Heine University ...

LVR-KLINIKUM DÜsseLDORF – hOsPITaL OF The heINRIch-heINe UNIVeRsITY DÜsseLDORF
Table 5: Research projects for the “Nicotine” Deutsche Forschungsgemeinschaft (DFG) Priority Programme with participation of the research units of the
Department of Psychiatry and Psychotherapy of the Heinrich-Heine University Düsseldorf
No. Project Participating research units
or co-workers
P3 Attention network, nicotine dependence and alpha4beta2
according to receptor genotype in healthy subjects and
schizophrenic patients.
P7 Effects of nicotine on social cognition and social stress in
schizophrenia.
P10 Genetics of nicotine dependence – clinical and neurobiological
phenotypes in a multi-centre case-controlstudy.
P12 Molecular and physiological effects of nicotine in the central
nervous system (SPP coordination)
PM=Project management
carried out in the initial funding period from 2006 to 2008. Other
institutions were associated with the priority programme as
cooperation partners. During this period, the LVR-Klinikum
Düsseldorf hosted a coordination project directed by the coordinator
of the priority programme, G. Winterer. Elsewhere, the
Neuropsychiatric Research Laboratory ran two projects as
well another project related to the programme, in cooperation
with the Experimental Psychopathology Research Laboratory.
Descriptions of these projects can be found in the report
sections of both research laboratories.
SUCHTFORSCHUNGSVERBUND NRW
3.1.1.5 Dependence Research Network
64
North Rhine-Westphalia (FMER)
Spokesperson: W. Gaebel (from 2006), M. Gastpar
(LRA Clinic, Essen, until 2006)
The Dependence Research Network North Rhine-Westphalia
is one of four national dependence research networks that
were funded by the FMER from 2001 to 2007. One of the
projects designed and directed by the Dependence Disorders
Research group of the LVR-Klinikum Düsseldorf was
related to the interaction of anti-craving substances with
behavioural therapy in the outpatient treatment of persons
with alcohol dependence and was realised from 2002 to
2007 as one of a total of seven research projects within
the context of this network. The LVR-Klinikum Düsseldorf
has subsequently been a member of this network of the
dependence research groups of the Universities of Essen,
Bonn and Münster, set up in 1996. After the retirement of
the previous spokesperson, M. Gastpar (Essen), in 2006, W.
Gaebel took over this position.
Participation
status
Neuropsychiatric Research Laboratory PM
RL Experimental Psychopathology;
Neuropsychiatric Research Laboratory
PM
Neuropsychiatric Research Laboratory PM
Neuropsychiatric Research Laboratory PM
3.1.1.6 “Psychotherapy of Psychotic Syndromes”
Research Network (FMER)
Centre director: W. Wölwer
The “Psychotherapy of Psychotic Syndromes” Research
Network investigates whether disorder-specific cognitive
behavioural therapy (CBT) can lead to an improvement
in psychotic positive symptoms (delusionary ideas and
hallucinations) and investigates its mode of action. The
central project was a multi-centre, randomised clinical
trial investigating the efficacy and mode of action of
psychotherapy – in addition to pharmacological treatment
– on positive symptoms in psychotic disorders. In
addition, studies were carried out to evaluate economic
aspects, to study the interaction of neurobiological and
psychosocial factors and to determine the applicability of the
aforementioned forms of treatment in adolescent patients,
and detailed analyses were performed of mediators and
moderators in the psychotherapeutic process. The research
network is coordinated by S. Klingberg and G. Buchkremer
of the University of Tübingen and includes the eight
university departments for psychiatry and psychotherapy in
Bonn, Düsseldorf, Essen, Frankfurt, Köln, Leipzig, Marburg
and Tübingen. Since 2006, the network has been funded by
the German Federal Ministry for Education and Research
(FMER). The Experimental Psychopathology Research
Laboratory is involved in five projects (Table 6) and the
Neuropsychiatric Research Laboratory in a further one.