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Impact of - IDL-BNC @ IDRC - International Development Research ...

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However, based on individual complaints, there were significant differences<br />

between exposed and control populations with regard to neuropsychiatric<br />

and certain other problems. Complaints regarding skin conditions were more<br />

commonly reported in the exposed rural group and chest and upper respiratory<br />

tract dysfunction was more common among the urban exposed group.<br />

Abdominal complaints were similar for all groups.<br />

Medical examinations revealed significantly more neurological, psychiatric,<br />

and liver disorders among the exposed groups.<br />

Polyneuropathy was significantly more common among exposed workers<br />

(37.33%) than in the control group (7%). The typical clinical presentation was<br />

a worker with several years' exposure, complaining <strong>of</strong> general ill-health,<br />

paresthesia (30.33% <strong>of</strong> all exposed workers), impotence (18.67%), depressed<br />

tendon reflexes, stock and glove hypoesthesia with muscle twitches and<br />

hypotonia occurring in some <strong>of</strong> the workers. Optic neuropathy and diminution<br />

<strong>of</strong> visual acuity were found, especially among the rural exposed workers.<br />

The polyneuropathy was generally mild and mainly sensory, although there<br />

was evidence <strong>of</strong> more severe neuropathy with distal wasting and weakness<br />

<strong>of</strong> the muscles <strong>of</strong> both the upper and the lower limbs in some cases. All<br />

neurological findings were more prominent among older workers and those<br />

exposed for a longer period. Neurobehavioural symptoms and signs in the<br />

exposed workers appeared to be related to duration <strong>of</strong> exposure.<br />

Abdominal abnormalities were more common in the rural exposed group.<br />

Enlargement <strong>of</strong> the liver was frequent and associated in some with tenderness,<br />

more characteristic <strong>of</strong> pesticide intoxication than bilharziasis. On the other<br />

hand, signs related to the cardiorespiratory system, including atherosclerosis<br />

and hypertension with cardiac asthma, were more common among the urban<br />

workers (p

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