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Impact of - IDL-BNC @ IDRC - International Development Research ...

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carbons (e.g., DDT) suggests that neuropsychiatric changes and liver damage<br />

(detected by ultrasonography or biochemical parameters) in the rural group<br />

<strong>of</strong> workers might be due to this group <strong>of</strong> pesticides.<br />

Contact dermatitis and allergic sensitization have been observed frequently<br />

in pesticide workers after exposure to a variety <strong>of</strong> pesticides (Adams 1983).<br />

Photoallergic reactions have been reported as well (WHO 1989). The number<br />

<strong>of</strong> cases in exposed workers in this study differed significantly from the control<br />

group, but the numbers were small.<br />

It was difficult to determine the degree or duration <strong>of</strong> exposure to specific<br />

pesticides. Workers were shifted from department to department as vacancies<br />

occurred, and formulation <strong>of</strong> pesticides in both establishments depended on<br />

market factors. However, the overall results demonstrated the existence <strong>of</strong><br />

hazardous working conditions in the two plants.<br />

Signs and symptoms <strong>of</strong> acute and chronic pesticide exposure were prominent,<br />

particularly for organophosphate and carbamate insecticides and for the<br />

exposed group <strong>of</strong> rural workers, for whom a reduction in AChE activity <strong>of</strong><br />

more than 50% was recorded in 62% <strong>of</strong> workers. Liver dysfunction was<br />

observed in 90% <strong>of</strong> exposed workers, but the significance <strong>of</strong> this in terms <strong>of</strong><br />

acute and chronic toxicity effects remains unclear because <strong>of</strong> the endemicity<br />

<strong>of</strong> bilharzia. There was good evidence <strong>of</strong> significant chronic toxicity in the<br />

form <strong>of</strong> neurologic disorders.<br />

The results <strong>of</strong> this study indicate the need to improve safety in the working<br />

environment and to train workers in the safe handling <strong>of</strong> pesticides.<br />

Acknowledgment- This work was supported by a grant from the <strong>International</strong><br />

<strong>Development</strong> <strong>Research</strong> Centre, Canada.<br />

Adams, R.M. 1983. Occupational skin diseases. Grun and Stratton, New York, NY,<br />

USA.<br />

Alber, G.V. 1976. Zbravookhkirg, 2, 38.<br />

Amr, M.M.; El-Batanouni, M.M.; El-Gendy, M.; Gaafer, T. 1984a. Some cardiorespiratory<br />

and haematological manifestations due to exposure to zinc phosphide<br />

(ZnPO4). Egyptian Journal <strong>of</strong> Occupational Medicine, 8(2), 131-141.<br />

Amr, M.M.; Abbas, E.Z.; El Samra, G.H.; Ayed, FA. 1984b. Clinical and biochemical<br />

evaluation <strong>of</strong> hazards in workers occupationally exposed to zinc phosphide<br />

pesticide. Medical Journal <strong>of</strong> Cairo University, 52(2).<br />

Amr, M.M.; et al. 1984c. Some metabolic studies among workers exposed to zinc<br />

phosphide (ZnPO4) during its preparation in Egypt. Journal <strong>of</strong> Occupational<br />

Medicine, 8(2), 211-222.<br />

128

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