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(12) PATENT APPLICATION PUBLICATION
(19) INDIA (21) Application No.: 1185/MUM/2004 A
(22) Date of filing of Application: 04/11/2004 (43) Publication Date: 09/06/2006
(54) Title of the invention: PROCESS FOR THE PREPARATION OF CRYSTALLINE FORM II OF
CLARITHROMYCIN
(51) International classification : A61kK3/70,
C07H 1/00,
17/08
(31) Priority Document No : NIL
(32) Priority Date : NIL
(33) Name of priority country : NIL
(86) International Application No : NIL
and Filing Date : NIL
(87) International Publication No : NIL
(61) Patent of addition to :
Application No
NIL
(62)
Filed on : N.A.
Divisional to Application No : NIL
Filed on : N.A.
(71) Name of Applicant:
GLENMARK PHARMACEUTICALS
LIMITED
Address of the Applicant:
B/2, MAHALAXMI CHAMBERS, 22,
BHULABHAI DESAI ROAD, POST
BOX NO.26511, MUMBAI-400 026,
INDIA.
(72) Name of the Inventor:
1. BOBBA VENKTA SIVA KUMAR
2. SHEKHAR BHASKAR BHIRUD
3. CHANGDEV NAMDEV RAUT.
Filed U/S 5(2) before The Patents
(Amendment) Act, 2005: NO
(57) Abstract: A process for preparing Form II crystals of clarithromycin is provided comprising (a) treating
clarithromycin with a carboxylic acid in an organic solvent to provide a clarithromycin acid salt; and, (b) heating
the clarithromycin acid salt under vacuum and at a temperature capable of providing Form II crystals of
clarithromycin.
Drawing: 01 Sheet.
Total Pages: 18.
Fig. Nil
The Patent Office Journal 09/06/2006 10874