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(12) PATENT APPLICATION PUBLICATION
(19) INDIA (21) Application No.: 1267/MUM/2004 A
(22) Date of filing of Application: 25/11/2004 (43) Publication Date: 09/06/2006
(54) Title of the invention: A DRY MTHOD FOR SURFACE MODIFICATION OF SU-8 FOR
IMMOBILIZATION OF BIOMOLECULES USING HOTWIRE
INDUCED PYROLYTIC PROCESS
(51) International classification : G01N 33/543,
FG01N
(31) Priority Document No : NIL
(32) Priority Date : NIL
(33) Name of priority country : NIL
(86) International Application No : NIL
and Filing Date : NIL
(87) International Publication No : NIL
(61) Patent of addition to :
Application No
NIL
(62)
Filed on : N.A.
Divisional to Application No : NIL
Filed on : N.A.
(71) Name of Applicant:
INDIAN INSTITUTE OF
TECHNOLOGY
Address of the Applicant:
POWAI, MUMBAI 400076, STATE OF
MAHARASHTRA, INDIA.
(72) Name of the Inventor:
1. SOUMYO MUKERJI
2. RAKESH LAL
3. RAMGOPAL RAO
4. DUSANE R.O.
5. MANOJ JOSHI
6. NITIN KALE
Filed U/S 5(2) before The Patents
(Amendment) Act, 2005: NO
(57) Abstract: Biosensors and bioreactors require immobilization of biological molecules within the device. With
advancements of microfabrication techniques and substrates such as silicon, its derivatives (e.g. silicon dioxide,
silicon nitride, etc.) and noble metals like gold. Off late the polymer called SU-8 (Glycidyl ether of bisphenol A)
has attracted attention due to the fact that low Young’s modules and/or high aspect ratio structures can be created
using SU-8. However there was a lack of processes to immobilize biomolecules on SU-8. The method developed
and described in this document pertains to a novel and inexpensive method modifying the SU-8 surface in order to
make it amenable to immobilization of biomolecules. Further this invention provides SU-8 substrates with
biomolecules (e.g. antibody, antigen, DNA, RNA, and Enzymes etc.) immobilized on the surface.
Drawing: 14 Sheets.
Total Pages: 37.
Fig. Nil
The Patent Office Journal 09/06/2006 10925