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(12) PATENT APPLICATION PUBLICATION
(19) INDIA (21) Application No.: 1221/MUM/2004 A
(22) Date of filing of Application: 10/11/2004 (43) Publication Date: 09/06/2006
(54) Title of the invention: A SUSTAINED RELEASE FORMULATION OF STAVUDINE
(51) International classification : A61K 9/22,
A61K 31/7072
A61P 31/18
(31) Priority Document No : NIL
(32) Priority Date : NIL
(33) Name of priority country : NIL
(86) International Application No : NIL
and Filing Date : NIL
(87) International Publication No : NIL
(61) Patent of addition to :
Application No
NIL
(62)
Filed on : N.A.
Divisional to Application No : NIL
Filed on : N.A.
(71) Name of Applicant:
EMCURE PHARMACEUTICALS
LIMITED
Address of the Applicant:
EMCURE HOUSE, T-184, M.I.D.C.,
BHOSARI, PUNE-411 026,
MAHARASHTRA, INDIA.
(72) Name of the Inventor:
1. MRS.MANJUSHA JOSHI
2. SHRIKANT PIMPLE
3. AMOL KAWLE
4. SATISH RAMANLAL MEHTA
Filed U/S 5(2) before The Patents
(Amendment) Act, 2005: NO
(57) Abstract: This invention relates to a composition and the process for the preparation of a sustained release
matrix tablet of Stavudine, characterized in that the composition comprises Stavudine with dissolution modifier(s)
in the form of a hydrophilic swellable polymer, diluent, binder and lubricant comprising the process steps of,
blending the active ingredient, dissolution modifier(s), diluent(s) and binder(s), granulating the blend using a
granulating fluid, drying the wet mass at 30ºC to 50ºC, lubricating with a lubricant and compressing the lubricated
granules into a tablet
Drawing: 03 Sheets.
Total Pages: 49.
Fig. Nil
The Patent Office Journal 09/06/2006 10895