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(12) PATENT APPLICATION PUBLICATION
(19) INDIA (21) Application No.: 01201/KOLNP/2005 A
(22) Date of filing of Application: 22/06/2005 (43) Publication Date: 09/06/2006
(54) Title of the invention: DEVICES AND METHOD FOR DIRECT ELECTRICAL DETECTION OF MOLECULES AND
MOLECULE-MOLECULE INTERACTIONS
(51) International classification : G01N 33/53
(31) Priority Document No : 10/335,043
(32) Priority Date : 31/12/2002
(33) Name of priority country : USA
(86) International Application No and : PCT/US03/041778
Filing Date
: & 31/12/2003
(87) International Publication No : WO 04/061421
(61) Patent of addition to Application No : NA
Filed on : NA
(62) Divisional to Application No : NA
Filed on : NA
(57) Abstract:
An analysis device includes an electrode arrangement, a
current/voltage provider, and a circuit analyzer. The electrode
arrangement has an interdigitated electrode pair including a first
electrode and a second electrode. Coupled to the electrode
arrangement is a signal generator adapted to provide a signal (e.g., an
alternating current or voltage) having a selected range of frequencies.
The analyzer is coupled to the electrode arrangement and is operative
to analyze an electrical parameter of the circuit as the signal is
applied. An analytic method includes measuring changes in one or
more parameters of the circuit over the range of frequencies. By such
measurement, the device can determine whether a target moiety has
been bound by a probe attached to the electrode(s). The device can
also specifically identify the intermolecular system detected, i.e., by
'finger-printing ' the electrical response of each molecule or
intermolecular complex.
(Fig. 3)
(71) Name of Applicant:
OREGON HEALTH & SCIENCES UNIVERSITY.,
Address of the Applicant:
2525 SW 1 ST AVENUE, SUITE 120, PORTLAND,
OREGON 97201-4753, USA.
(72) Name of the Inventor:
1) VANDENBARK ARTHUR A.
2) SOLANKI RAJENDRA
Filed U/S 5(2) before The Patents (Amendment)
Act, 2005: NO
The Patent Office Journal 09/06/2006 11082