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PATENT APPLICATION PUBLICATION
INDIA
Date of filing of Application:17/02/2005
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Application No.: 615/DELNP/2005
Publication Date:09/06/2006
(54) Title of the Invention:. STROMAL CELL-DERIVED FACTOR –1 MEDIATES STEM CELL HOMING
AND TISSUE REGENERATION IN ISCHEMIC CARDIOMYOPATHY
(51) International Classification : A61K 31/70
(31) Priority Document No.
:
60/405,274
60/426,712
(32) Priority Date : 22/08/2002
30/04/2003
(33) Name of priority country US
(86) International application No. : PCT/US2003/026013
Filing Date : 21/08/2003
(87) International Publication No. : WO 2004/017978
(61) Patent of Addition to
Application No.
:
N.A.
(62) Divisional to Application No. : N.A
Filed On :
Total No. Pages : 84
(71)Name of Applicant: THE
CLEVELAND CLINIC FOUNDATION
Address of the Applicant:
9500 EUCLID AVENUE, CLEVELAND,
OH 44122, USA
(72) Name of the Inventor: :
PENN, MARC S
ASKARI ARMAN T
KIEDROWSKI MATTHEW
Filed U/S 5(2) before The Patents
(Amendment) Ordinance, 2004 : NO
(57) Abstract: method of treating infarcted myocardial tissue includes, the concentration of SDF-1 protein in the infarcted tissue.
The concentration of stem cells in the peripheral blood of the infarcted tissue is also increased. The number of stem cells in the
peripheral blood is increased while the concentration of SDF-1 in the infarcted tissue is increased.
The Patent Office Journal 09/06/2006 11125
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