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(12) PATENT APPLICATION PUBLICATION
(19) INDIA (21) Application No.: 00398/KOLNP/2005 A
(22) Date of filing of Application: 11/03/2005 (43) Publication Date: 09/06/2006
(54) Title of the invention: BMP-2 ESTROGEN RESPONSIVE ELEMENT AND METHODS OF USING THE SAME
(51) International classification : C07H 21/04,C12N
15/63,15/85,15/86,
C12Q 168
(31) Priority Document No : 60/404,024
(32) Priority Date : 16/08/2002
(33) Name of priority country : US
(86) International Application No and : PCT/US03/23271
Filing Date
: 18/08/2003
(87) International Publication No : WO 04/016639 A1
(61) Patent of addition to Application No : NIL
Filed on : N.A.
(62) Divisional to Application No : NIL
Filed on : N.A.
(57) Abstract:
(71) Name of Applicant:
WYETH
Address of the Applicant:
FIVE GIRALDA FARMS MADISON NJ 07940
USA
(72) Name of the Inventor:
1.BODINE PETER VAN NEST
2.GAZIT DAN
Filed U/S 5(2) before The Patents (Amendment)
Act, 2005: NO
The invention relates to an isolated nucleic acid corresponding to BMP-2 regulatory region, or a fragment thereof comprising an estrogen
responsive element, vector comprising the same and cells, which comprises said vector. In another embodiment, the invention provides
methods of identifying an estrogen agonist, antagonist and a therapeutic agent in another embodiment the invention provides methods of
treating conditions which are associated with estrogen insufficiency or with lack of response to external estrogen or agonists thereof.
(FIG. Nil)
The Patent Office Journal 09/06/2006 10989