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(12) PATENT APPLICATION PUBLICATION
(19) INDIA (21) Application No.: 01106/KOLNP/2005 A
(22) Date of filing of Application: 09/06/2005 (43) Publication Date: 09/06/2006
(54) Title of the invention: PRION PROTEIN LIGANDS AND METHODS OF USE
(51) International classification : C12N
(31) Priority Document No : 60/430,423
(32) Priority Date : 03/12/2002
(33) Name of priority country : US
(86) International Application No and : PCT/US03/038343
Filing Date
: 03/12/2003
(87) International Publication No : WO 04/050851 A2
(61) Patent of addition to Application No : NIL
Filed on : N.A.
(62) Divisional to Application No : NIL
Filed on : N.A.
(57) Abstract:
(71) Name of Applicant:
THE AMERICAN NATIONAL RED CROSS &
NORTH CAROLINA STATE UNIVERSITY
Address of the Applicant:
15601 CRABBS BRANCH WAY ROCKVILLE
MD 20855 USA & 2401 RESEARCH DRIVE
SUITE 1122 RALEIGH NC 27695-8212 USA
(72) Name of the Inventor:
1. HAMMOND DAVID J
2. LATHROP JULIA T
3. CERVENAKOVA LARISA
4. CARBONELL RUBEN G
Filed U/S 5(2) before The Patents (Amendment)
Act, 2005: NO
Ligands that bind to prion proteins and methods for using the ligands for detecting or removing a prion protein from a sample, such as a
biological fluid or an environmental sample. The ligands are capable of binding to one or more forms of prion protein including cellular
prion protein (PrPc), infectious prion protein (PrPsc), and recombinant prion protein (PrPr). Prions from various species, including
humans and hamsters, are bound by the ligands. Also provided is a method of treating or retarding the development of a prion-associated
pathology in a subject.
(FIG. -NIL)
The Patent Office Journal 09/06/2006 11078