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(12) PATENT APPLICATION PUBLICATION
(19) INDIA (21) APPLICATION No:
1296/MAS/1997A
(22) Date of filing of Application:16/06/1997 (43) Publication Date: 09/06/2006
(54) Title of the invention:
MODIFIED BIOCOMPATIBLE SPONGE
FOR IMPROVED ABSORPTION OF
TISSUE FLUIDS AND SURGICAL
RECONSTRUCTION
(51)International classification:C08J
009/30, A61K 035/32, A61K 038/39
(31) Priority Document No.
(32) Priority Date:
(33) Name of priority country:
(87) WIPO No. :
(61) Patent of addition to
Application No. :
Filed on:
(62) Divisional to
Applcation No.:
Filed on:
(71) Name of Applicant
SREE CHITRA TIRUNAL INSTITUTE
FOR MEDICAL SCIENCES &
TECHNOLOGY
Address of Applicant:
, BIOMEDICAL TECHNOLOGY WING,
SATELMOND PALACE,
THIRUVANANTHAPURAM - 695 012,
INDIA,
INDIA
(72) Name of the Inventor(s):
PRABHA DAMODARAN NAIR
RAJAGOPALAN SIVAKUMAR
(57)Abstract
This invention relates to a process for preparing modified
biocompatible sponge comprising in the steps of :
a. preparing a solution of the polyvinyl alcohol of high visco- sity;
b. adding to the solution of the polyvinyl a surfactant such as herein described;
c. mixing the solution of PYA and surfactant with an acidic solution of chitosan followed by frothing the mixture thus
obtained;
d. adding an aldehyde crosslinker such as herein described and an acid catalyst to crosslink the PYA and the chitosan
to obtain the biocompatible sponge.
The Patent Office Journal 09/06/2006 10811