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(12) PATENT APPLICATION PUBLICATION
(19) INDIA (21) Application No.: 00646/KOLNP/2005 A
(22) Date of filing of Application: 18/04/2005 (43) Publication Date: 09/06/2006
(54) Title of the invention: CRYSTAL STRUCTURE OF PIM-1 KINASE
(51) International classification : C12N 9/12
(31) Priority Document No : 60/411,398
60/412,341
(32) Priority Date : 16/09/2002
20/09/2002
(33) Name of priority country : USA
(86) International Application No and : PCT/US03/029415
Filing Date
: & 16/09/2003
(87) International Publication No : WO 04/024895
(61) Patent of addition to Application No : NA
Filed on : NA
(62) Divisional to Application No : NA
Filed on : NA
(57) Abstract:
A crystal structure of PIM-1 is described that was determined by Xray
crystallography. The use of PIM-1 crystals and structural
information can, for example, be used for identifying molecular
scaffolds and for developing ligands that bind to and modulate PIM-1
and other PIM kinases.
(FIG). 1
(71) Name of Applicant:
PLEXXIKON, INC
Address of the Applicant:
91 BOLIVAR DRIVE, SUITE A
BERKLEY, CA 94710, USA.
(72) Name of the Inventor:
1. BREMER, RYAN
2. IBRAHIM, PRABHA N
3. KUMAR, ABHINAV
4. MANDIYAN, VALSAN
5. MILBURN, MICHAEL V
Filed U/S 5(2) before The Patents (Amendment)
Act, 2005: NO
The Patent Office Journal 09/06/2006 11004