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Graphique 1 - Faculté de Médecine et de Pharmacie de Fès

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ABSTRACT<br />

Systemic lupus erythematosus SLE is a systemic autoimmune disease with<br />

multiorgan involvement of a complex pathoa<strong>et</strong>iology and a great clinical<br />

polymorphism.<br />

The haematological abnormalities observed in SLE are commun, varied and<br />

well established in the literature. Nearly all SLE patients <strong>de</strong>velop some<br />

haematological manifestation during the course of the disease.<br />

Haematologic involvement is a part of the revised criteria of the American<br />

Rheumatism Association ARA and is <strong>de</strong>fined by:<br />

• Hemolytic anemia,<br />

• Leukopenia less than 4x10 9 /l on two or more occasions,<br />

• Lymphopenia

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