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Convened under the auspicious of esteemed endorsers - ISTA

Convened under the auspicious of esteemed endorsers - ISTA

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Results:We found a surprisingly high prevalence <strong>of</strong> lesions on MRI scan in <strong>the</strong> well functioning group(11 out 23, 48%) when compared to <strong>the</strong> painful group (79 out <strong>of</strong> 137, 57%). However, <strong>the</strong>rewere a significantly greater number <strong>of</strong> grade 1 lesions in <strong>the</strong> well functioning group. Wesuggest that <strong>the</strong>se are post-surgical changes and should not be confused with pathological,tissue destroying lesions.DiscussionThis is <strong>the</strong> largest ever study <strong>of</strong> patients with MARS MRI scans <strong>of</strong> MOM hips. It is <strong>the</strong> first touse a classification system and <strong>the</strong> first to compare well functioning with painful hips. We arenow able to provide radiologists and surgeons with clinical interpretation <strong>of</strong> a lesion on MRIscan. Our classification system will provide useful information on both symptomatic andasymptomatic patients. Longitudinal follow up <strong>of</strong> <strong>the</strong>se patients will provide <strong>the</strong> final validation.Thursday, October 7, 2010, 9:00-9:50Session A2: Alternate Bearings in THA 2Synchrotron Xray Spectroscopy Reveals Chemical Form <strong>of</strong> in-HumanMetal-on-Metal Hip Wear Debris : Ultima and Current Generation HipsSummary*Alister Hart - Imperial College - London, UKPaul Quinn - Diamond - Harwell, UKJohn Nolan - Norwich - Norwich, UKKeith Tucker - Norwich - Norwich, UKJohn Skinner - Royal National Orthopaedic Hospital Trust - Stanmore, UKJonathan Powell - Cambridge - Cambridge, UKFerdinand Lali - Imperial College - London, UKFred Mosselmans - Diamond - Harwell, UK*Email: a.hart@imperial.ac.ukWe report <strong>the</strong> first use <strong>of</strong> synchrotron xray spectroscopy to characterize and compare <strong>the</strong>chemical form and distribution <strong>of</strong> metals found in tissues surrounding patients with metal-onmetalhip replacements that failed with (Ultima hips) or without (current generation, largediameter hips) corrosion.IntroductionThe commonest clinical category <strong>of</strong> failure <strong>of</strong> metal-on-metal (MOM) hip replacements is“unexplained” and commonly involved a s<strong>of</strong>t tissue inflammatory response. The mechanism <strong>of</strong>failure <strong>of</strong> <strong>the</strong> Ultima MOM total hip replacement includes severe corrosion <strong>of</strong> <strong>the</strong> metal stemand was severe enough to be removed from clinical use. Corrosion is not a feature that we havefile:///E|/<strong>ISTA</strong>2010-Abstracts.htm[12/7/2011 3:15:47 PM]

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