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Poster: 3Comparison of Different Modalities of Post Operative Analgesia inUnilateral Total Knee Replacement Patients*Mohammad Ashik - Singapore General Hospital - Singapore, Singapore*Email: ashik76@gmail.comIntroduction: We report the results of a prospective randomised trial comparing differentmodalities of post operative analgesia in unilateral total knee replacement(TKR) patients.Methods: 90 patients aged between 50 to 80 years undergoing unilateral TKR were randomisedinto 3 groups.Group 1:. Patients only received patient controlled morphine analgesia (PCA). (control)Group 2: Patients received PCA and intra-articular marcaine via continuous infusion pump.Group 3: Patients received PCA and intra-operative periarticular injection of steroid andmarcaine.Visual analogue pain scores (VAS) , morphine consumption via PCA, number of days toambulation, active range of movement(AROM) of operated knee, and length of stay(LOS) werethe primary outcomes measured.Results:Adequate pain control achieved in all 3 arms.Group 3 demonstrates :1. significant reduction in pain scores (p= 0.002) in the first 6 hours post surgery.2. Significant reduction in the total morphine usage (p=0.042).3. Decreased LOS compared to Group 1 (p=0.006) and Group 2 (p=0.01)The number of days to ambulation, and AROM of the operated knee during the inpatient staywere similar in all 3 groups.The mean duration of surgery for Group 2 (100min +/- 23) wassignificantly longer compared to the other groups (p=0.03). After 24 months of follow up, nopost surgical complications (eg, infection) were demonstrated in this study.Conclusion: The periarticular injection of analgesia with steroid appears to be a safe andeffective modality for pain control post TKR and demonstrates superiority over both controland infusion arms.file:///E|/ISTA2010-Abstracts.htm[12/7/2011 3:15:47 PM]