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Cambridge International A Level Biology Revision Guide

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Chapter 10: Infectious diseases<br />

Roll Back Malaria<br />

Malaria is one of the most serious of all human<br />

diseases. It is endemic in about 100 countries in Latin<br />

America, Africa and South-East Asia. An infectious<br />

disease is endemic in a country if it is maintained there<br />

by transmission between people and does not occur<br />

by being brought into the country by travellers. The<br />

burden of malaria is felt most in countries in Africa:<br />

47% of all deaths from malaria occur in Nigeria and the<br />

Democratic Republic of the Congo.<br />

If we are to lift the burden of malaria, then we<br />

have to outsmart this disease. Many international<br />

organisations are cooperating with African<br />

governments to reduce the number of cases of<br />

malaria. For example, Roll Back Malaria is a global<br />

partnership working to implement coordinated action<br />

against malaria. Laboratory research using modern<br />

genetic methods plays an important part, but the<br />

success of new initiatives in the Roll Back Malaria<br />

campaign can only be evaluated by tracking cases of<br />

the disease and collecting accurate data. Technology is<br />

helping here too in pinpointing accurately where cases<br />

occur (Figure 10.1). Find out more by searching online<br />

for ‘roll back malaria’.<br />

Knowing when and where outbreaks occur provides<br />

key data in the fight against infectious diseases. When<br />

an outbreak of malaria occurs, the local population<br />

can be warned to take appropriate precautions to<br />

avoid getting bitten by mosquitoes. These include<br />

sleeping under bed nets and draining any bodies<br />

of water that female mosquitoes might use to lay<br />

their eggs. The local area can be sprayed to kill any<br />

mosquitoes. By tracking when and where malaria<br />

outbreaks occur, health agencies can direct their<br />

resources to control the spread of the disease and limit<br />

its effects on local populations.<br />

Figure 10.1 Modern technology in the fight against malaria:<br />

these health workers in Kenya are using GPS to record<br />

accurate locations where there are outbreaks of malaria.<br />

199<br />

Infectious diseases are diseases that are caused by<br />

organisms known as pathogens. They are sometimes<br />

called communicable diseases as they are passed from<br />

infected to uninfected people. Some also affect animals<br />

and are passed from animals to humans.<br />

In Chapter 9, we considered non-infectious diseases<br />

of the gas exchange and cardiovascular systems, such as<br />

lung cancer and COPD. These are long-term degenerative<br />

diseases. They are non-infectious diseases, as they are not<br />

caused by pathogens. Inherited or genetic diseases, such as<br />

cystic fibrosis and sickle cell anaemia, are another group of<br />

non-infectious diseases. There are other categories of noninfectious<br />

disease, including deficiency diseases that are<br />

caused by malnutrition and mental diseases.<br />

The word ‘disease’ implies something very serious,<br />

yet many conditions that make us feel ill, such as the<br />

common cold, are not as harmful to health as the diseases<br />

discussed in this chapter. ‘Disease’ is a difficult word to<br />

define satisfactorily as it covers a wide range of human<br />

conditions. A working definition is given below.<br />

A disease is an illness or disorder of the body or mind that<br />

leads to poor health; each disease is associated with a set<br />

of signs and symptoms.<br />

As you read this chapter and Chapter 11, you can think of<br />

ways to improve this definition.<br />

QUESTION<br />

10.1 Use Chapter 9 and this chapter to name:<br />

a two infectious diseases and two non-infectious<br />

diseases of the gas exchange system<br />

b two non-infectious diseases of the cardiovascular<br />

system.

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