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Cambridge International A Level Biology Revision Guide

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<strong>Cambridge</strong> <strong>International</strong> A <strong>Level</strong> <strong>Biology</strong><br />

Answers to self-assessment questions<br />

Man and the child with blood group B: I B I o<br />

Woman and the child with blood group A: I A I o<br />

Child with blood group O: I o I o<br />

11 Suitable symbols for these four alleles could be:<br />

C A to represent the agouti allele<br />

C g to represent the chinchilla (grey) allele<br />

C h to represent the Himalayan allele<br />

C a to represent the albino allele<br />

a C A C A agouti<br />

C A C g agouti<br />

C A C h agouti<br />

C A C a agouti<br />

C g C g chinchilla<br />

C g C h chinchilla<br />

C g C a chinchilla<br />

C h C h Himalayan<br />

C h C a Himalayan<br />

C a C a albino<br />

b i The genotype of the albino parent must<br />

be C a C a , as the allele C a is recessive to<br />

everything else. Each of the offspring will<br />

therefore get a C a allele from this parent.<br />

The offspring are all chinchilla, so their<br />

genotypes must all be C g C a . This means<br />

that the chinchilla parent must have<br />

given a C g allele to each offspring, so the<br />

chinchilla parent almost certainly has the<br />

genotype C g C g . If it had any other allele in<br />

its genotype, this would be expected to<br />

show in the phenotype of its offspring.<br />

When the C g C a offspring are crossed, they<br />

will produce genotypes C g C g , C g C a and<br />

C a C a in a ratio of 1 : 2 : 1; that is, a ratio of<br />

chinchilla to albino in a ratio of 3 : 1. This<br />

is close enough to the actual ratio of 4<br />

chinchilla to 2 albino, as with these very<br />

small numbers it is unlikely for ratios to<br />

work out exactly.<br />

ii Following similar reasoning to that in i<br />

above, the agouti rabbit probably has the<br />

genotype C A C h , and the Himalayan parent<br />

the genotype C h C h . This would produce<br />

agouti and Himalayan offspring in a ratio<br />

of 1 : 1.<br />

iii As chinchilla rabbits are produced in the<br />

first generation, at least one of the agouti<br />

parents must carry a chinchilla allele. As<br />

a Himalayan rabbit is produced in the<br />

Parental<br />

phenotype<br />

Parental<br />

genotype<br />

second generation, one of the original<br />

parents must carry a Himalayan allele.<br />

The first cross is therefore:<br />

agouti<br />

C A C h<br />

agouti<br />

C A C g<br />

Gametes C A or C h C A or C g<br />

Offspring<br />

C A C A<br />

agouti<br />

C A C h<br />

agouti<br />

C A C g<br />

agouti<br />

C h C g<br />

chincilla<br />

The second cross, between two chinchilla<br />

rabbits with the genotype C h C g , would be<br />

expected to produce offspring with the<br />

genotypes C h C h , C h C g and C g C g in a ratio of<br />

1 : 2 : 1,so giving the phenotypic ratio of 3<br />

chinchilla to 1 Himalayan.<br />

12 Parental phenotype female male<br />

Parental genotype XX XY<br />

Gametes X X or Y<br />

Offspring<br />

XX<br />

female<br />

XY<br />

male<br />

13a No. The son will receive a Y chromosome<br />

from his father, which cannot carry a<br />

haemophilia allele.<br />

b Yes. The man could pass on his haemophilia<br />

allele to a daughter, who could then pass it<br />

on to a son.<br />

14a Suitable symbols could be:<br />

X N allele for normal colour vision<br />

X n allele for red-green colour blindness<br />

X N X N normal female<br />

X N X n carrier (normal) female<br />

X N Y normal male<br />

X n Y male with colour blindness<br />

b<br />

Parental phenotype normal normal<br />

Parental genotype X N X n X N Y<br />

Gametes X N or X n X N or Y<br />

<strong>Cambridge</strong> <strong>International</strong> AS and A <strong>Level</strong> <strong>Biology</strong> © <strong>Cambridge</strong> University Press 2014

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