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Cambridge International A Level Biology Revision Guide

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<strong>Cambridge</strong> <strong>International</strong> A <strong>Level</strong> <strong>Biology</strong><br />

The black bear’s big sleep<br />

It is metabolically expensive for a mammal to maintain<br />

a constant, warm body temperature in long winters<br />

when it is very cold and food is hard to find. Black<br />

bears feed well during the summer to build up stores<br />

of energy-rich fat (Figure 14.1). In the autumn and<br />

early winter, the bears dig dens for themselves, or<br />

find a ready-made one in somewhere like a cave,<br />

curl up and sleep until the weather improves. Their<br />

metabolism adjusts for this lengthy period of inactivity<br />

when they do not eat, drink, urinate or defecate.<br />

Their stores of fat and some muscle protein provide<br />

energy. The waste product of protein breakdown is<br />

urea, which is filtered from the blood by the kidneys.<br />

The kidneys continue to produce urine, but it is all<br />

reabsorbed by the bladder. The urea cannot be stored;<br />

instead it is recycled by the bear’s gut bacteria. These<br />

break it down to ammonia and carbon dioxide,<br />

which are absorbed into the blood. Carbon dioxide is<br />

breathed out and ammonia combined with glycerol<br />

from the breakdown of fat to make amino acids.<br />

The amino acids are used to synthesise the enzymes<br />

that are needed in larger quantities for the increased<br />

hydrolysis of fat during the bear’s hibernation.<br />

Figure 14.1 During the summer, black bears build up stores<br />

of fat for survival during the seven months or so when they do<br />

not eat.<br />

300<br />

To function efficiently, organisms have control systems to<br />

keep internal conditions near constant, a feature known as<br />

homeostasis. This requires information about conditions<br />

inside the body and the surroundings, which are detected<br />

by sensory cells. Some of the physiological factors<br />

controlled in homeostasis in mammals are:<br />

■■<br />

■■<br />

■■<br />

■■<br />

■■<br />

■■<br />

core body temperature<br />

metabolic wastes, particularly carbon dioxide and urea<br />

blood pH<br />

blood glucose concentration<br />

water potential of the blood<br />

the concentrations in the blood of the respiratory gases,<br />

oxygen and carbon dioxide.<br />

First, we will look at the need for mammals to maintain a<br />

stable internal environment, and then consider how they<br />

maintain a constant core body temperature.<br />

Internal environment<br />

The internal environment of an organism refers to all<br />

the conditions inside the body. These are the conditions<br />

in which the cells function. For a cell, its immediate<br />

environment is the tissue fluid that surrounds it.<br />

Many features of the tissue fluid influence how well the<br />

cell functions. Three features of tissue fluid that influence<br />

cell activities are:<br />

■■<br />

■■<br />

■■<br />

temperature – low temperatures slow down metabolic<br />

reactions; at high temperatures proteins, including<br />

enzymes, are denatured and cannot function<br />

water potential – if the water potential decreases, water<br />

may move out of cells by osmosis, causing metabolic<br />

reactions in the cell to slow or stop; if the water<br />

potential increases, water may enter the cell causing it<br />

to swell and maybe burst<br />

concentration of glucose – glucose is the fuel for<br />

respiration, so lack of it causes respiration to slow or<br />

stop, depriving the cell of an energy source; too much<br />

glucose may cause water to move out of the cell by<br />

osmosis, again disturbing the metabolism of the cell.<br />

In general, homeostatic mechanisms work by controlling<br />

the composition of blood, which therefore controls the<br />

composition of tissue fluid. See page 164 to remind<br />

yourself how this happens. There are control mechanisms<br />

for the different aspects of the blood and tissue fluid. These<br />

include the three physiological factors listed above.

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