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Cambridge International A Level Biology Revision Guide

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<strong>Cambridge</strong> <strong>International</strong> A AS <strong>Level</strong> and A <strong>Biology</strong> <strong>Level</strong> <strong>Biology</strong><br />

528<br />

disaccharides, 31–2<br />

discontinuous variables, 258<br />

discontinuous variation, 399–400<br />

discrete variables, 494<br />

discussion, 506<br />

disease, 199<br />

autoimmune, 237–8<br />

defence against, 223–4<br />

incidence of, 200<br />

infectious, 198–218<br />

non-infectious, 199<br />

prevalence of, 200<br />

disruptive selection, 404<br />

dissociation curve, 168<br />

distal convoluted tubule, 306, 311<br />

disulfide bonds, 42<br />

division of labour, 5<br />

DNA (deoxyribonucleic acid), 5, 95<br />

electrophoresis, 470–1<br />

mitochondrial (mtDNA), 416–17<br />

protein synthesis, 118, 119–22<br />

recombinant (rDNA), 463, 466<br />

replication, 113–18<br />

semi-conservative replication, 113,<br />

117<br />

structure, 111–13<br />

triplet codes, 118–19, 513<br />

DNA ligase, 466<br />

domains, 435–8<br />

dominant alleles, 376, 377<br />

dopamine, 193, 341<br />

dormancy, 356<br />

double circulation, 160<br />

double helix, 113<br />

double reciprocal plot, 62–3<br />

doxycycline, 204<br />

drawings, 129, 262<br />

ecosystems, 425<br />

ectotherms, 269<br />

Eden Project, 454<br />

effector, 30<br />

efferent arteriole, 306<br />

elastin, 191–2<br />

electrocardiograms (ECGs), 178<br />

electrochemical gradient, 322, 334<br />

electromagnetic spectrum, 10–11<br />

electron micrograph, 10<br />

electron microscope, 3, 10, 11–12<br />

electron transport chain, 273–5<br />

electrophoresis, 469–71<br />

elephants, 442<br />

embryo sac, 372<br />

embryo transfer, 448<br />

emphysema, 191–2<br />

emulsion test, 38<br />

end-product inhibition, 61–2<br />

endangered species, 445–50<br />

endemic diseases, 200<br />

endocrine glands, 349<br />

endocytosis, 77, 87, 88<br />

endodermis, 132, 144<br />

endoplasmic reticulum (ER), 15<br />

endosperm, 356<br />

endosymbiont theory, 17<br />

endothelium, 161, 307<br />

endotherms, 269<br />

energy, 268–9, 270, 287–8<br />

energy density, 278–9<br />

Ensembl, 475<br />

enzymes, 53–66<br />

activation energy, 56–7<br />

active site, 54<br />

affinities, 62–4<br />

enzyme–product complex, 55<br />

enzyme–substrate complex, 54<br />

factors affecting action, 57–62<br />

immobilised, 64<br />

induced fit hypothesis, 55<br />

inhibition of, 61–2<br />

intracellular and extracellular, 54<br />

lock and key hypothesis, 54–5<br />

mode of action, 54–7<br />

pH and, 60<br />

substrates, 54, 59<br />

temperature and, 59–60<br />

turnover rate, 62<br />

V max<br />

, 59, 62, 64<br />

epidemics, 200<br />

epidermal impressions, 137<br />

epidermal peels, 137<br />

epidermis, 131, 145<br />

epithelium, 161<br />

error bars, 499<br />

error sources, 255, 261<br />

erythrocytes, 166–7<br />

Escherichia coli, 111, 118, 390<br />

ester, 37<br />

ester bond, 37<br />

ethylene glycol, 61<br />

euchromatin, 96<br />

Eukarya, 436, 437<br />

eukaryotes, 21, 22, 391<br />

evaluation, 504–5<br />

evolution, 404–9, 412–13<br />

excretion, 304<br />

exercise, 278<br />

exocytosis, 87, 88<br />

expansins, 355<br />

experiments, 247<br />

planning of, 491–5<br />

extinctions, 417–18<br />

extrinsic proteins, 76<br />

eyepiece graticule, 7<br />

F1 and F2 generations, 377<br />

facilitated diffusion, 82<br />

factor VIII, 379, 476<br />

FAD (flavin adenine dinucleotide), 275<br />

fat stores, 38<br />

fatty acids, 36–7<br />

fibres, 34–5, 44<br />

fibrillation, 178<br />

fibrils, 44<br />

fibrous proteins, 43, 44<br />

fingerprinting, 470–1<br />

fitness, 403<br />

fluid mosaic model, 74–6<br />

follicle stimulating hormone, 351<br />

founder effect, 408<br />

Franklin, Rosalind, 113<br />

frequency diagram, 258<br />

frozen zoo, 448<br />

fungi, 438<br />

G proteins, 78<br />

G 1<br />

and G 2<br />

phases, 97<br />

Galapagos Islands, 446<br />

gametes, 94, 371<br />

gametogenesis, 371–2<br />

gas exchange, 186–90<br />

gel electrophoresis, 469–71<br />

gene mutations, 387–9, 398<br />

gene technology, 462–86<br />

gene therapy, 477–80<br />

genes, 15, 95, 118, 119, 366, 367, 374,<br />

375–7<br />

genetic diagrams, 376<br />

genetic diversity, 426<br />

genetic drift, 408<br />

genetic engineering, 463–75<br />

genetic profiling (fingerprinting), 470–1<br />

genetic screening, 476–7<br />

genetic variation, 367, 398–9<br />

genetically modified organism, 463,<br />

480–5<br />

genetics, 368, 374<br />

genotype, 374–5<br />

geographical isolation, 414<br />

germ cell gene therapy, 480<br />

GFP (green fluorescent protein), 468<br />

giant panda, 447<br />

gibberellins, 354, 355–6, 391<br />

glands, 349<br />

glasshouse crops, 292<br />

global warming, 443<br />

globin, 43<br />

globular glycoproteins, 228<br />

globular proteins, 43<br />

glomerular filtration rate, 308<br />

glomerulus, 306, 307<br />

glucagon, 315, 317

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