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Cambridge International A Level Biology Revision Guide

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<strong>Cambridge</strong> <strong>International</strong> A <strong>Level</strong> <strong>Biology</strong><br />

Pressure was applied to the Pacinian corpuscle and recordings made of the electrical activity in the axon at<br />

microelectrodes A and B. The results are shown in the diagram below.<br />

recordings from microelectrode A recordings from microelectrode B<br />

40<br />

40<br />

Light<br />

pressure<br />

20<br />

Potential difference<br />

0<br />

across membrane / mV<br />

–20<br />

–40<br />

20<br />

0<br />

–20<br />

–40<br />

–60<br />

40<br />

1 2 3<br />

–60<br />

40<br />

1 2 3<br />

20<br />

20<br />

Medium<br />

pressure<br />

Potential difference 0<br />

across membrane / mV<br />

–20<br />

–40<br />

0<br />

–20<br />

–40<br />

362<br />

–60<br />

60<br />

1 2 3<br />

–60<br />

60<br />

1 2 3<br />

40<br />

40<br />

20<br />

20<br />

Heavy<br />

pressure<br />

0<br />

Potential difference<br />

across membrane / mV<br />

–20<br />

–40<br />

–60<br />

0<br />

–20<br />

–40<br />

–60<br />

–80<br />

1 2 3<br />

Time / ms<br />

–80<br />

1 2 3<br />

Time / ms<br />

a Suggest what happened in the unmyelinated region of the axon as pressure was applied to the<br />

Pacinian corpuscle. [4]<br />

b Explain the pattern of recordings from microelectrode B as the pressure applied to the corpuscle<br />

was increased. [4]<br />

c Explain why sensory neurones from Pacinian corpuscles are myelinated and not unmyelinated. [3]<br />

[Total: 11]

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