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Cambridge International A Level Biology Revision Guide

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<strong>Cambridge</strong> <strong>International</strong> AS <strong>Level</strong> <strong>Biology</strong><br />

Answers to end-of-chapter questions<br />

b distribution for one mark:<br />

malaria occurs between the tropics / tropics<br />

and sub-tropics / in equatorial regions / South<br />

and Central America, Africa and S-E Asia;<br />

explanation for four marks:<br />

Anopheles / mosquito / vector, distributed<br />

throughout tropical regions;<br />

Plasmodium falciparum cannot complete its<br />

life cycle within mosquitoes at temperatures<br />

less than 20 °C;<br />

Anopheles, needs high rainfall / high humidity<br />

/ standing water;<br />

Anopheles lays eggs in water;<br />

no transmission at high altitude;<br />

too cold for parasite to complete life cycle;<br />

no transmission in deserts;<br />

no breeding grounds for mosquitoes;[max. 5]<br />

c Plasmodium is intracellular parasite;<br />

inside, red blood cells / liver cells;<br />

antigenic concealment;<br />

antibodies are ineffective;<br />

short stage in plasma when antibodies are<br />

effective;<br />

Plasmodium is eukaryotic;<br />

has many, genes / antigens;<br />

difficult to develop a vaccine;<br />

resistance to drugs used, to treat malaria / as<br />

prophylactics;<br />

example of drug;<br />

Anopheles / vector, breeds in small pools of<br />

water;<br />

difficult to control all breeding places;<br />

mosquitoes come into contact with humans;<br />

mosquitoes become resistant to insecticides;<br />

[max. 6]<br />

[Total: 14]<br />

8 a bacteria pass out in faeces of infected<br />

person;<br />

carried in, water / food, consumed by<br />

uninfected person;[2]<br />

b i 2.22;[1]<br />

ii treatment for cholera involves supply of<br />

oral rehydration therapy;<br />

and provision of safe drinking water;<br />

better response to emergencies (in some<br />

countries);<br />

effectiveness of response may depend on<br />

number of cases;<br />

ref to very high number of cases in Haiti;<br />

may depend on remoteness of regions<br />

affected by cholera;<br />

or ways in which, emergency supplies /<br />

personnel, can reach affected areas;<br />

ref to high case fatality rates in, Nigeria /<br />

Cameroon;<br />

use of data to compare case fatality rates<br />

in individual country with global rate;<br />

[max. 3]<br />

iii cholera is a serious disease;<br />

death can occur very quickly after infection;<br />

spreads quickly in population (especially<br />

after a disaster);<br />

deaths are avoidable;<br />

if ORT is available immediately;<br />

data is useful to predict, situations /<br />

places, where cholera may occur;<br />

WHO can coordinate responses to<br />

outbreaks; [max. 3]<br />

c i infected person travelled from an area with<br />

an outbreak of cholera;[1]<br />

ii water supply is not contaminated with<br />

(human), sewage / faeces;<br />

piped water / water supply is treated to<br />

kill bacteria;<br />

V. cholera destroyed in sewage treatment;<br />

[max. 2]<br />

[Total: 12]<br />

9 a i Mycobacterium tuberculosis; accept<br />

Mycobacterium bovis[1]<br />

ii infected person, coughs / sneezes / spits;<br />

aerosol / droplets, containing bacteria,<br />

breathed in by uninfected person;[2]<br />

b i Sub-Saharan Africa;<br />

South-East Asia;<br />

countries of, old Soviet Union / Russian<br />

Federation;<br />

India / Pakistan / Afghanistan;<br />

South America / Bolivia;<br />

Papua New Guinea; [max. 3]<br />

ii TB linked with HIV infection;<br />

HIV weakens immune system;<br />

TB is an opportunistic disease;<br />

<strong>Cambridge</strong> <strong>International</strong> AS and A <strong>Level</strong> <strong>Biology</strong> © <strong>Cambridge</strong> University Press 2014

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