Cambridge International A Level Biology Revision Guide

Cambridge International A Level Biology
Recommended resources
Chapter 19
Further reading
Alberts, B. et al. (2013) Essential Cell Biology, 4th edn. Garland Science.
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Chapter 10: ‘Modern Recombinant DNA Technology’ including ‘Polymerase chain reaction’,
a clear animation.
Available at: www.garlandscience.com/ECB4-students.
Brown, T.A. (2007) Genomes 3. Garland Science.
See the topics in the section ‘Classical Genetics’.
Online and interactive resources
www.sciberbrain.org
www.sciberbrain.org/advanced-level
The Biochemical Society has set up a special website for education. There is an advanced-level
animated presentation on genetic engineering. A lower-level presentation (standard level) is also
available for a gentler introduction.
www.hhmi.org/biointeractive
BioInteractive is a free resource for teachers and students, including animations, short films and
apps. (HHMI in the web address refers to the Howard Hughes Medical Institute.)
www.hhmi.org/biointeractive/polymerase-chain-reaction
This is a step-by-step animation explaining the polymerase chain reaction.
www.hhmi.org/biointeractive/genetic-engineering
An animation showing how a new gene can be inserted into a loop of bacterial DNA (a plasmid). A
restriction enzyme is shown cutting the DNA, allowing a new piece of DNA to be inserted.
www.hhmi.org/biointeractive/human-genome-sequencing
An animation outlining the principles adopted when trying to sequence the human genome.
www.abpischools.org.uk/object/download.cfm?lib=liPoster&id=409
This site contains notes on genetic engineering, including a clear and attractive downloadable
poster ‘Genetic Engineering – New Horizons in Medicine’. There is also a poster on the human
genome project. These posters are part of a useful series entitled ‘New Horizons in Medicine’.
www.dnalc.org/resources/animations/index.html
The DNA Learning Centre at the Cold Spring Harbor Laboratory has many animations on the topics
covered in this chapter.
www.dnaftb.org/
There are many resources to support topics in this chapter in the section in another website from
Cold Spring Harbor: DNA from the Beginning.
www.dnai.org
See the sections on ‘Manipulation’ and ‘Applications’.
Cambridge International AS and A Level Biology © Cambridge University Press 2014