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Cambridge International A Level Biology Revision Guide

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Contents<br />

16 Inherited change 364<br />

Homologous chromosomes 365<br />

Two types of nuclear division 367<br />

Meiosis 368<br />

Genetics 374<br />

Genotype affects phenotype 374<br />

Inheriting genes 375<br />

Multiple alleles 378<br />

Sex inheritance 378<br />

Sex linkage 379<br />

Dihybrid crosses 380<br />

Interactions between loci 382<br />

Autosomal linkage 383<br />

Crossing over 384<br />

The χ 2 (chi-squared) test 386<br />

Mutations 387<br />

Gene control in prokaryotes 389<br />

Gene control in eukaryotes 391<br />

End-of-chapter questions 393<br />

17 Selection and evolution 397<br />

Variation 398<br />

Natural selection 402<br />

Evolution 404<br />

Artificial selection 409<br />

The Darwin–Wallace theory of evolution by<br />

natural selection 412<br />

Species and speciation 413<br />

Molecular comparisons between species 416<br />

Extinctions 417<br />

End-of-chapter questions 420<br />

18 Biodiversity, classification and<br />

conservation 423<br />

Ecosystems 425<br />

Biodiversity 426<br />

Simpson’s Index of Diversity 430<br />

Systematic sampling 431<br />

Correlation 433<br />

Classification 435<br />

Viruses 440<br />

Threats to biodiversity 441<br />

Why does biodiversity matter? 444<br />

Protecting endangered species 445<br />

Controlling alien species 451<br />

<strong>International</strong> conservation organisations 452<br />

Restoring degraded habitats 453<br />

End-of-chapter questions 455<br />

19 Genetic technology 462<br />

Genetic engineering 463<br />

Tools for the gene technologist 464<br />

Genetic technology and medicine 475<br />

Gene therapy 477<br />

Genetic technology and agriculture 480<br />

End-of-chapter questions 487<br />

P2 Planning, analysis and evaluation 490<br />

Planning an investigation 491<br />

Constructing a hypothesis 491<br />

Using the right apparatus 491<br />

Identifying variables 492<br />

Describing the sequence of steps 495<br />

Risk assessment 495<br />

Recording and displaying results 495<br />

Analysis, conclusions and evaluation 495<br />

Pearson’s linear correlation 501<br />

Spearman’s rank correlation 503<br />

Evaluating evidence 504<br />

Conclusions and discussion 506<br />

End-of-chapter questions 507<br />

Appendix 1: Amino acid R groups 512<br />

Appendix 2: DNA and RNA triplet codes 513<br />

Glossary 514<br />

Index 526<br />

Acknowledgements 534<br />

CD-ROM<br />

Advice on how to revise for and approach<br />

examinations<br />

Introduction to the examination and changes<br />

to the syllabus<br />

Answers to self-assessment questions<br />

Answers to end-of-chapter questions<br />

Recommended resources<br />

CD1<br />

CD1<br />

CD16<br />

CD21<br />

CD64<br />

CD128<br />

v

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