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24/06/2005 - Controller General of Patents, Designs, and Trade Marks

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(12) PATENT APPLICATION PUBLICATION<br />

(19)<br />

INDIA (21) Application No: 956/MUMNP/2003 A<br />

(22) Date <strong>of</strong> filing <strong>of</strong> Application : 10/10/2003<br />

(54) Title <strong>of</strong> the invention:<br />

(51) International Classification: A 61 K 9/08 (71)<br />

(31) Priority Document No. : 1. 60/293,832<br />

2. 60/343,733<br />

(32) Priority Date :<br />

(33) Name <strong>of</strong> priority country :<br />

(86)<br />

(43) Publication Date: <strong>24</strong>/<strong>06</strong>/<strong>2005</strong><br />

METHOD FOR PREPARING A LIQUID PHARMACEUTICAL<br />

COMPOSITION.<br />

1. 25/05/2001<br />

2. 25/10/2001<br />

U.S.A.<br />

International Application : PCT/IB02/01500<br />

No. <strong>and</strong> Filing Date : 29/04/2002<br />

(87) International :<br />

Publication No. WO02/094220 A1<br />

(61)<br />

(62)<br />

Patent <strong>of</strong> addition to<br />

Application No. : NIL<br />

Filed on N.A.<br />

Divisional to<br />

Application No. : NIL<br />

Filed on : N.A.<br />

(72)<br />

Name <strong>of</strong> the Applicant:<br />

WARNER-LAMBERT COMPANY<br />

LLC.<br />

Address <strong>of</strong> the Applicant:<br />

201 TABOR ROAD,<br />

MORRIS PLAINS,<br />

NEW JERSEY 07950,<br />

UNITED STATES OF AMERICA.<br />

Name <strong>of</strong> the Inventors:<br />

1. KULKARNI NEEMA MAHESH<br />

2. SCHNEIDER MICHAEL<br />

3. SILBERING STEVEN BERNARD<br />

4. MEYER-WONNAY HANS RICHARD<br />

5. SANII-YAHYAI NAHID<br />

Filed U/S 5(2) before the<br />

<strong>Patents</strong> (Amendment)<br />

Ordinance,2004 : NO<br />

(57) Abstract : A liquid pharmaceutical composition <strong>of</strong> a GABA analog comprising at least one polyhydric alcohol<br />

containing 2 to 6 carbon atoms having a pH <strong>of</strong> about 5.5 to about 7.0 <strong>and</strong> additionally a two-component liquid<br />

pharmaceutical composition comprising a first component comprising a powder mixture comprising a GABA analog<br />

<strong>and</strong> a solid polyhydric alcohol, <strong>and</strong> a second component comprising a liquid base are described, as well as methods to<br />

prepare the compositions <strong>and</strong> a method for treating cerebral diseases, including epilepsy, faintness attacks, hypokinesia<br />

<strong>and</strong> cranial traumas, neurodegenerative disorders, depression, mania <strong>and</strong> bipolar disorders, anxiety, panic,<br />

inflammation, renal colic, insomnia, gastrointestinal damage, incontinence, pain, including neuropathic pain, muscular<br />

pain, skeletal pain, <strong>and</strong> migraine using a therapeutically effective amount <strong>of</strong> the pharmaceutical compositions.<br />

( Figure: NIL )<br />

Total Pages : 16.<br />

The Patent Office Journal <strong>24</strong>.<strong>06</strong>.<strong>2005</strong> 17844

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