24/06/2005 - Controller General of Patents, Designs, and Trade Marks

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(12) PATENT APPLICATION PUBLICATION
(19) INDIA (21) Application No.857/KOLNP/2003 A
(22) Date of filing of Application 02/07/2003 (43) Publication Date: 24/06/2005
(54) Title of the invention: “USE OF AN ADENOSINE
A3 RECEPTOR AGONIST FOR INHIBITOR OF
VIRAL REPLICATION”
(51) International classification: A61K 31/52
(31) Priority Document No: 60/261,659
(32) Priority Date: 16/01/2001
(33) Name of priority country: US
(86) International Application No and Filing Date:
PCT/IL02/00028 AND 13/01/2002
(87) International Publication No: WO 02/055085 A2
(61) Patent of addition to
Application No: NIL
filed on: NIL
(62) Divisional to
Application No: NIL
filed on: NIL
(71) Name of Applicant: CAN FITE
BIOPHARMA LTD
Address of the Applicant BAREKET
STREET 10,49170 PETACH
TIKVA,ISRAEL
(72) Name of the Inventor:
1. FISHMAN PNINA
2. KHALILI KAMEL
Filed U/S 5(2) before The Patents
(Amendment) Ordinance,2004 : YES
(57) Abstract:
Present invention concerns the use of an active ingredient selected from the group consisting of agnonists of
the adenosine receptor system, for inhibiting viral replication in cells. In particular, the invention provides a
composition and method for inhibiting viral replication in cells, the method comprising presenting to the
cells an effective amount of the active ingredient. According to one embodiment, the adenosine agonist is
an A3 receptor agonist (A3RAg). The invention is particularly useful, for although not limited to, inhibiting
the replication of HIV virus in human cells.
The Patent Office Journal 24.06.2005 18061