24/06/2005 - Controller General of Patents, Designs, and Trade Marks

Publication After 18 month
The following Patent application have been published under Section 11A of the Patents
(Amendment) Act, 2005
21) Application No.:
(54) Title of the invention:
537/MUMNP/2004
PCT/GB02/02964
Date:27/06/2002
(51) International classification: C 07 C 253/16 (71)
(30) Priority Data :
(31) Document No.: 0116212.2
(32) Date : 03/07/2001
(33) Name of convention country : GREAT
BRITAIN
(66) Filed U/s. 5(2) : NO
(61) Patent of addition to application No.: NIL
(62) Filed on : N.A.
(63) Divisional to Application No.: NO
(64) Filed on : N.A.
(57) Abstract:
A (22) Date of filing of
Application:
28/09/2004
PROCESS FOR THE PREPARATION OF NITRILE
COMPOUNDS.
(72)
Name of the Applicant:
PHOENX CHEMICALS LIMITED.
Address of the Applicant:
34 THURSBY ROAD,
CROFT BUSINESS PARK,
BROMBOROUGH, WIRRAL,
CH623PW,
GREAT BRITAIN.
Name of the Inventors
01. BLACKER ANDREW JOHN
02. HOUSON LAN NICHOLAS
03. WIFFEN JONATHAN
WILLIAM
A process is provided for the preparation of a compound of Formula (1) wherein: R is H,
optionally substituted acyl, optionally substituted alkyl, optionally substituted aryl or
optionally substituted heteroaryl: R and R each independently are H or a hydroxy
protecting group; comprising the steps: (a) reacting a compound of Formula (2) in a solvent in
the presence of a base with a compound of formula RSO2X to give a compound of
Formula (3); wherein: R is an optionally substituted alkyl, optionally substituted aryl or
optionally substituted heteroaryl group; and X is halogen: and (b) reacting the compound of
Formula (3) with a cyanide source in the presence of a phase transfer catalyst.
Figure: NIL
The Patent Office Journal 24.06.2005 17968