24/06/2005 - Controller General of Patents, Designs, and Trade Marks

Publication After 18 month
The following Patent application have been published under Section 11A of the Patents
(Amendment) Act, 2005
21) Application No.:
(54) Title of the invention:
538/MUMNP/2004
PCT/GB03/02192
Date: 21/05/2003
(51) International classification: C 07 C 67/31 (71)
(30) Priority Data :
(31) Document No.: 0211716.6
(32) Date : 22/05/2002
(33) Name of convention country : GREAT
BRITAIN
(66) Filed U/s. 5(2) : NO
(61) Patent of addition to application No.: NIL
(62) Filed on : N.A.
(63) Divisional to Application No.: NO
(64) Filed on : N.A.
(57) Abstract:
A (22) Date of filing of
Application:
CONTINUOUS PROCESS FOR THE
ENANTIOSELECTIVE CATALYTIC
HYDROGENATION OF BETA-KETOESTERS.
(72)
Name of the Applicant:
28/09/2004
PHOENX CHEMICALS LIMITED.
Address of the Applicant:
34 THURSBY ROAD,
CROFT BUSINESS PARK,
BROMBOROUGH, WIRRAL,
CH623PW,
GREAT BRITAIN.
Name of the Inventors
01. PROCTOR LEE DAVID
02. WARR ANTONY JOHN
The present invention relates to a continuous process for the enantioselective catalytic hydrogenation of B-
ketoesters comprising providing a catalytic hydrogenation zone and maintaining it under condition of
temperature and pressure effective for the catalytic hydrogenation of B- ketoesters; continuously supplying
to the catalytic hydrogenation zone a substrate comprising B- ketoesters to be hydrogenation a catalytic
effective for the enantioselective hydrogenation of B- ketoesters and hydrogen; contacting the substrate, the
catalytic and the hydrogen in the hydrogenation zone for a residence time effective for at least partial
enantioselective catalytic hydrogenation of B- ketoesters; (d) continuously withdrawing from the
hydrogenation zone a reaction product mixture comprising enantioselectively hydrogenation of B-
ketoesters, unreacted B- ketoesters, catalytic and hydrogenation; (e) supplying the reaction product mixture
to a separation zone and separating at least some of the enantioselectively hydrogenation of B- ketoesters
from the reaction product mixture; (f) withdrawing separted enantioselectively hydrogenation of B-
ketoesters as product; and (g)optionally supplying at least part of the remaining from the separation zone to
the hydrogenation zone.
Figure: NIL
The Patent Office Journal 24.06.2005 17969