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Food additives data book - wordpres

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LEGISLATION: USA: CANADA:<br />

GRAS for specified applications. For adults and For specific regulations, refer to Part D:<br />

children 4 years or older, Recommended Daily Vitamins, Minerals and Amino Acids of the<br />

Allowance is 300 mg of biotin <strong>Food</strong> and Drug Regulations, Health and Welfare<br />

Canada.<br />

UK and EUROPE: Recommended Daily Intake not available<br />

Recommended Daily Allowance is 0.15 mg biotin<br />

REFERENCES: Ash, M., and Ash, I. (1995) <strong>Food</strong> Additives: Electronic Hand<strong>book</strong>. Gower Publishing Company,<br />

Brookfield, VT, 05036, USA.<br />

Augustin, J., and Scarbrough, F. E. (1990) Nutritional Additives. In: Branen, A. L., Davidson, P. M.,<br />

and S. Salminen (Eds.), <strong>Food</strong> Additives, pp. 33–81.<br />

Budavari, S. (1996) The Merck Index, 12th edition.<br />

Health and Welfare Canada (1996) Part D: Vitamins, Minerals and Amino Acids. In: <strong>Food</strong> and Drug<br />

Regulations. Department of Health, Ottawa, ON, Canada.<br />

ANY OTHER RELEVANT INFORMATION: Potency of pure compound is 100%. The pure compound is stable to air and temperature. Moderately<br />

acid and neutral solutions are stable for several months; alkaline solutions are less stable, but appear<br />

reasonably stable up to a pH of about 9. Aqueous solutions are very susceptible to mould growth.<br />

Acidic solutions can be heat-sterilised<br />

Biotin 613

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