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Food additives data book - wordpres

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Preservatives 794<br />

NAME: Nisin<br />

CATEGORY: Antimicrobial preservative<br />

FOOD USE: Pasteurised cheese and cheese spreads/ Canned fruits and vegetables<br />

SYNONYMS: E234/ CAS 1414-45-5/ EINECS 215-807-5/ Streptococcus lactis (Lactococcus lactis) bacteriocin<br />

FORMULA: C143H230N42O37S7 (contains L-amino acids and the unusual sulphur-containing amino acids<br />

lanthionine and beta-methyllanthionine). There are five variants of nisin – A, B, C, D and E. The<br />

most active antimicrobially is variant A. The commercial product contains mainly variant A<br />

MOLECULAR MASS: 3500 (usually occurs as the dimer – 7000)<br />

ALTERNATIVE FORMS: Nisaplin ® is the tradename for nisin produced by Aplin & Barrett Ltd., Dorset, England<br />

PROPERTIES AND APPEARANCE: Crystals derived from pure culture fermentation of Streptococcus lactis (Lactococcus lactis)<br />

PURITY %: Not less than 900 international units per mg<br />

WATER CONTENT MAXIMUM IN %: 3.0<br />

HEAVY METAL CONTENT MAXIMUM IN 10<br />

ppm:<br />

ASH MAXIMUM IN %: Not less than 50% NaCl<br />

SOLUBILITY % AT VARIOUS TEMPERATURE/pH COMBINATIONS:<br />

in water: @ pH 2.5 12.0 @ pH 5.0 4.0 @ >pH 7.0 Insoluble<br />

FUNCTION IN FOODS: As a preservative in cheese and canned fruits and vegetables. Effective against Gram-positive<br />

bacteria, lactic acid bacteria, Streptococcus, Bacillus, Clostridium<br />

ALTERNATIVES: Other anti-botulinal antimicrobial preservative treatments

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