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Food additives data book - wordpres

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Nutritive Additives 640<br />

NAME: Folic acid<br />

CATEGORY: Nutritive additive<br />

FOOD USE: Breakfast cereals/ Fruit drinks/ Dietary supplement/ Dietetic foods/ Egg products/ Flour/ Formulated<br />

liquid diets/ Infant formulae/ Meal replacements/ Milk drinks/ Sugar and cocoa confectionery/<br />

Peanut spreads<br />

SYNONYMS: Folacin/ Folate/ Pteroylglutamic acid/ Vitamin M/ CAS 59-30-3/ EINECS 200-419-0<br />

FORMULA: C19H19N7O6<br />

MOLECULAR MASS: 441.4<br />

ALTERNATIVE FORMS: Folinic acid or citrovorum factor; pteroyltriglutamic acid; pteroylheptaglutamic acid; 7,8-dihydro- or<br />

5,6,7,8-tetrahydrofolic<br />

PROPERTIES: Odourless; not heat-stable<br />

APPEARANCE: Yellow to orange crystalline powder<br />

MELTING POINT (°C): No melting point; darkens and chars at 250<br />

SOLUBILITY % AT VARIOUS TEMPERATURE/pH COMBINATIONS:<br />

in water: @ 25°C Very slightly (0.0016 mg/ml) @ 100°C about 1%<br />

in ethanol solution: Insoluble<br />

FUNCTION IN FOODS: Enrichment, fortification or restoration<br />

TECHNOLOGY OF USE IN FOODS: Serial dilution may be required; optimum pH is 6–9<br />

ANTAGONISTS: Oxygen; light; reducing agents; labile to acid and light when in solution; heat lability depends on the<br />

type of compound, the pH of the heating medium, and the presence or absence of reducing agents<br />

FOOD SAFETY ISSUES: Toxicology: LD50 (IV, rat) = 500 mg/kg; folacin has a low toxicity for humans

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